Zalutumumab in Head and Neck Cancer

Exclusion Criteria

• •Received certain other treatments within 4 weeks prior to administration of study drug
• •Previous severe allergic reactions (e.g. angio-edema, severe asthma, or anaphylaxis).
• •Skin disease requiring systemic or local corticosteroid therapy.
• •Known brain metastasis or leptomeningeal disease.
• •Signs or symptoms of acute illness.
• •Bacterial, fungal or viral infection.
• •Certain serious medical conditions, including kidney or liver disease, some psychiatric illnesses, myocardial infarction within one year and stomach, lung, heart, hormonal, nerve or blood diseases.
• •Pregnant or breast-feeding women.
• •Women of childbearing age who are unable or unwilling to use an IUD or hormonal birth control during the whole trial.
• •Simultaneous participation in any other trial involving investigational drugs or having participated in a trial within 4 weeks prior to start of trial treatment.