High-Dose 3-Dimensional Conformal Radiation Therapy in Treating Patients With Inoperable Stage I, Stage II, or Stage IIIA Non-Small Cell Lung Cancer

Inclusion Criteria

• •DISEASE CHARACTERISTICS:
• •Histologically or cytologically confirmed non-small cell lung cancer
• •* Medically inoperable stage I or II disease
• •* Stage III disease eligible provided the following are true:
• •* No supraclavicular node involvement
• •* No peripherally located lower lobe tumor AND contralateral upper mediastinal node involvement
• •No distant metastasis
• •No malignant pleural or pericardial effusion
• •PATIENT CHARACTERISTICS:
• •Age
• •Not specified
• •Performance status
• •WHO 0-2
• •Life expectancy
• •Not specified
• •Hematopoietic
• •Not specified
• •Hepatic
• •Not specified
• •Renal
• •Not specified
• •Cardiovascular
• •No prior myocardial infarction
• •No prior complete bundle branch block
• •No other prior cardiovascular disease resulting in New York Heart Association class III or IV heart disease
• •No clinically significant cardiac arrhythmias
• •No congestive heart failure
• •Pulmonary
• •FEV\_1 at least 1.2 L OR
• •DLCO at least 60%
• •Other
• •No other prior or concurrent malignancy except cured basal cell skin cancer or carcinoma in situ of the cervix
• •No intractable or uncontrolled infection
• •No psychological, familial, social, or geographical condition that would preclude study compliance and follow-up
• •Able to tolerate a course of radiotherapy
• •PRIOR CONCURRENT THERAPY:
• •Biologic therapy
• •Not specified
• •Chemotherapy
• •At least 3 weeks since prior chemotherapy
• •No prior anthracyclines
• •No concurrent chemotherapy
• •Endocrine therapy
• •Not specified
• •Radiotherapy
• •No prior radiotherapy to the chest area
• •Surgery
• •No prior therapeutic surgery to the chest area
• •Other
• •No other prior therapy to the chest area