Treatment of Wegener's Granulomatosis With Cyclophosphamide

Inclusion Criteria

• •Patients greater than 1 year of age with the clinical and pathological diagnosis of WG whose illness presents a risk of permanent disability or death. Examples of processes that impart risk of permanent disability or death include: peripheral and central nervous system disease, cardiac involvement, glomerulonephritis, and vascular comprise of gastrointestinal organs.
• •No women who are pregnant or intend to become pregnant.
• •No patients who have known malignancies.
• •Patients must be HIV negative.