Fate Clinical Trials

CONTACT

Lead Sponsor

Fate Therapeutics

Age

12 - 70 years

Sex

ALL

Healthy Volunteers

No

•Age: 12 to 70 years old.
•Diagnosis: Must have active B-cell mediated autoimmune disease (SLE, AAV, IIM, or SSc) confirmed by standard criteria.
•Disease Severity: Moderate to severe, requiring at least two prior treatments that were ineffective.
•Health Status: Adequate organ function to tolerate treatment.
•Consent: Able to provide informed consent or assent/obtain parental consent and comply with study procedures.

•Pregnancy/Breastfeeding: Women must not be pregnant or nursing.
•Severe Organ Dysfunction: Significant heart, lung, liver, or kidney impairment.
•Active Infections: No recent or ongoing serious infections.
•Recent Cancer or Prior Cell Therapy: No active/recent malignancies, prior CAR T-cell therapy, or organ transplant.
•Allergies: No known allergies to study treatments.
•Weight Restriction: Must weigh at least 50 kg (110 lbs).