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1–20 of 8,295
Completed
Minimally Invasive Liver Surgery for Metastases From Colorectal Cancer: Oncologic Outcome and Prognostic Factors
Only few reports exist on long-term survival after minimally invasive liver surgery (MILS for colorectal liver metastases.
NCT01356706
·
Leuven, Vlaams-Brabant
Unknown
Intracorporeal Anastomosis in Laparoscopic Left Colectomy. Cohort Comparative Study
OBJECTIVE: The aim of the study is to demonstrate that the intracorporeal resection and anastomosis in left-sided colon cancer, sigma and upper rectum, is not inferior to…
NCT04456933
·
Sabadell, Barceelona
Unknown
Effect of Losartan on the Incidence and Severity of Chemotherapy-Induced Mucositis in Gastrointestinal Cancer Patients
Mucositis is a common and clinically significant side effect of both anticancer chemotherapy and radiation therapy that can affect any portion of the gastrointestinal tract.
NCT05871333
·
Cairo
Unknown
OPTIMOX1 in Chinese mCRC Patients
Previous OPTIMOX1 study investigated the use of oxaliplatin discontinuation and reintroduction in a novel stop-and-go strategy.
NCT01023633
·
Nanjing, Jiangsu and 1 other
Completed
Second Line ColoRectal Cancer Therapy in Combination With Combination of FOL- Folinic Acid(Leucovorin), F - Fluorouracil and OX - Oxaliplatin (FOLFOX)
The primary purpose of this study is to compare the efficacy of AZD2171 in combination with FOLFOX to the efficacy of bevacizumab in combination with FOLFOX, in the second-line…
NCT00278889
·
Innsbruck and 42 others
Completed
A Study of Avastin (Bevacizumab) in Combination With Xelox and Tarceva in Patients With Metastatic Colorectal Cancer.
This study will evaluate the efficacy and safety of a first-line regimen of Avastin and Xelox (Xeloda + Eloxatin) followed by Avastin and Tarceva, in patients with metastatic…
NCT01135498
·
Palma de Mallorca, Balearic Islands and 11 others
Completed
Risk Factors Associated With Morbidity and Mortality in Emergency Colorectal Cancer Resections
Study is designed to investigate the risk factors associated with morbidity and mortality in patients who underwent emergency resection because of colorectal cancer in general…
NCT06074432
·
Istanbul
Unknown
QoLiCOL - Quality of Life in Colon Cancer
All patients presenting at participating hospitals during the recruitment period with a newly diagnosed colon cancer, regardless of stage and planned treatment, will be eligible…
NCT02530593
·
Gothenburg
Completed
Phase I/II Study of Celebrex and EPO906 in Patients With Metastatic Colorectal Cancer
This study is for people with advanced colorectal cancer. This study uses the drugs Celebrex and EPO906.
NCT00159484
·
Los Angeles, California
Completed
Impact of a Novel Patient Educational Booklet on Colonoscopy Quality
Background: Achievement of colonoscopy outcomes depends on high-quality bowel preparation by patients; yet inadequate preparation is common.
NCT00975247
·
Los Angeles, California
Completed
Combination Chemotherapy in Treating Patients With Stage III Ovarian Epithelial Cancer or Gastrointestinal Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.
NCT00005049
·
New York, New York
Active not recruiting
Plasma Multi - Omics Detection for Evaluating Efficacy and Recurrence Risk in Oligometastatic Colorectal Cancer Conversion Therapy
This prospective study (PMEIRR-OCCCT) evaluates the utility of plasma multi-omics-including circulating tumor DNA (ctDNA), cell-free RNA (cfRNA), proteomics, and metabolomics-in…
NCT07492238
·
Shenyang, Liaoning
Completed
Perioperative MVT-5873, a Fully Human Monoclonal Antibody Against a CA 19-9 Epitope, for Operable CA 19-9 Producing Pancreatic Cancers, Cholangiocarcinomas, and Metastatic Colorectal Cancers
Background: Gastrointestinal tumors have a molecule called carbohydrate antigen 19-9 (CA19-9) in the tumors and blood. The agent MVT-5873 was designed to block this molecule.
NCT03801915
·
Bethesda, Maryland
Completed
Genetic Investigation of Solid Tumors Cohort
The objective of this study is to obtain blood samples, solid tumor and/or benign hyperplasia samples to learn more about genetic differences that are linked to the formation of…
NCT01005225
·
San Diego, California
Unknown
NK Activity Modulation Induced by Intravenous Lidocaine During Colorectal Laparoscopic Surgery
Surgical resection is the best treatment option for colorectal cancer. Despite this radical approach, recurrences within five years are still common.
NCT01841294
·
Montreal, Quebec
Terminated
Interventional Study of INCB 99280 With Ipilimumab in Participants With Select Solid Tumors
The purpose of this study is to characterize the safety, tolerability, PK, and efficacy of INCB 99280 in combination with ipilimumab in participants with select solid tumors.
NCT05909995
·
Los Angeles, California and 7 others
Recruiting
Isunakinra Alone and in Combination With Pembrolizumab in Patients With Colorectal Cancer (MSS)
This study will enroll patients with colorectal cancer that is locally advanced or metastatic.
NCT06634875
·
Los Angeles, California and 1 other
Recruiting
Phase 1 Study Evaluating the Safety and PK of ADU-1805 in Advanced Solid Tumors
This first-in-human, open-label, multicenter, multi-arm dose-escalation study is designed to evaluate the safety, PK, and PD of ADU-1805, an anti- SIRPα monoclonal antibody, as…
NCT05856981
·
Detroit, Michigan and 6 others
Recruiting
Circulating Tumor DNA Methylation Guiding Postoperative Adjuvant Chemotherapy in Stage III Colorectal Cancer
The goal of this randomized controlled trial is to investigate whether ctDNA methylation is a more precise indicator to guide postoperative adjuvant chemotherapy in stage Ill…
NCT06167967
·
Hanzhou, Zhejiang
Completed
Impact of Immunonutrition on Nutritional Status in Colorectal Cancer Patients
Colorectal cancer is among the top three types of cancer that are most common and causes death worldwide.Nutritional support is widely used in elective colorectal surgery…
NCT05568316
·
Istanbul, Uskudar
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