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1–20 of 4,468
Completed
Comparison of Veliparib and Whole Brain Radiation Therapy (WBRT) Versus Placebo and WBRT in Adults With Brain Metastases From Non-Small Cell Lung Cancer
The primary objective of this study is to evaluate the efficacy and safety of veliparib and whole brain radiation therapy in adults with brain metastases from non-small cell lung…
NCT01657799
Completed
Study to Evaluate the Safety and Efficacy of Serplulimab Plus Bevacizumab and Chemotherapy in NSCLC Patients With Brain Metastases
A multicenter, single-arm, open study to evaluate the safety and efficacy of Serplulimab in combination with bevacizumab and first-line chemotherapy in driver negative…
NCT05807893
·
Guangzhou, Guangdong
Recruiting
Use of [18F] Fluoroethyl-L-tyrosine PET/MRI for Identifying Small Functional Pituitary Adenomas
The purpose of this research is to evaluate the diagnostic role and clinical efficacy of investigational FET-PET/MRI in detecting MRI-occult primary or residual/recurrent…
NCT07456878
·
Jacksonville, Florida
Unknown
Effect of Dexmedetomidine on Plasmatic Cortisol Response in Transsphenoidal Surgery
Use of dexmedetomidine in pituitary tumor resection surgery as adjuvant drug and its relation to cortisol levels during postoperative period.
NCT02549768
·
Santiago, Santiago Metropolitan
Recruiting
Cerebellar Mutism Syndrome Study
The purpose of this study is to determine why up to 25% of the pediatric patients who have surgery for a tumor in the posterior fossa develops the Cerebellar Mutism Syndrome (CMS).
NCT02300766
·
Vienna and 31 others
Completed
Identify the Benefits CAREGIVERSPRO-MMD Platform Use Based on the Information and Communications Technology, Dedicated to the Support and Assistance of Dyads Living With Neurocognitive Diseases and Their Primary Caregivers
Our main goal is to test a web platform accessible by computers, smartphones and tablets, addressed specifically to caregivers and people with mild cognitive deterioration or mild…
NCT03536975
·
Elbeuf and 1 other
Recruiting
New Approach to Objectively Measure Social Engagement in Older Adults With Hearing Loss
The goal of this clinical trial is to learn if hearing devices, like hearing aids, affect social and cognitive function of older adults.
NCT06781749
·
Los Angeles, California and 1 other
Completed
Propofol-remifentanyl Versus Dexmedetomidine in Awake Craniotomy: Impact on Electroclinical Seizure Activity
Awake craniotomy require a cooperative patient during resection neurosurgery phase.
NCT05103735
·
Udine
Unknown
Evaluating Structural and Functional Changes of Brain by fMRI and DTI in Patients With Intracranial Germ Cell Tumors
BOLD-fMRI and DTI scans are performed to patients with germ cell tumors in the basal ganglia before and after treatments.
NCT03771625
·
Beijing
Not yet recruiting
Diagnostic Performance and Quantitative Analysis of [18F]FET PET in Brain Tumours
This is a retrospective study encompassing all \[18F\]FET PET scans performed at our centre.
NCT07599917
Unknown
Proteome-based Immunotherapy of Lung Cancer Brain Metastases
Trial Hypothesis: Acute, progressing lethal neurooncological process can be transferred into chronic and non-lethal, the survival rates and life quality can be improved by of…
NCT01782287
·
Moscow
Completed
Phase 2 Trial in Multiple Brain Metastases Outcomes With HA-SIB-WBRT
Recently, the evidence supports hippocampal avoidance with whole brain radiotherapy (HA-WBRT) as the recommended treatment option in patients with good prognosis and multiple…
NCT04452084
·
Singapore
Recruiting
A Study of 177Lu-DTPA-Omburtamab in Children and Adolescents With Brain Cancer or Cancer That Has Spread to the Central Nervous System (CNS)
The purpose of this study is to find out whether 177Lu-DPTA-omburtamab is a safe treatment for children and adolescents with recurrent/refractory medulloblastoma or another type…
NCT07698899
·
Basking Ridge, New Jersey and 6 others
Completed
Everolimus (RAD001) Therapy for Epilepsy in Patients With Tuberous Sclerosis Complex (TSC)
The goal of this study is to learn if the study drug RAD001 can reduced the number of epileptic seizures, and can be taken safety by people who have epilepsy associated with…
NCT01070316
·
Cincinnati, Ohio and 1 other
Recruiting
Prophylactic Oral Antibiotics on Sinonasal Outcomes Following Endoscopic Transsphenoidal Surgery for Pituitary Lesions
To find out whether oral antibiotics given after transsphenoidal endoscopic surgery for pituitary adenoma improves sinus and nasal symptoms, reduces the incidence of infection…
NCT03014687
·
Phoenix, Arizona
Recruiting
MRI Screening for Brain Metastases Among Patients With Triple Negative or HER2+ Stage II or III Breast Cancer
The goal of this multi-centre, prospective study is to assess the frequency of asymptomatic brain metastasis in patients with stage IIb or III Triple Negative or HER2 positive…
NCT06247449
·
Toronto, Ontario
Unknown
Radiation Therapy With or Without Temozolomide in Treating Women With Brain Metastases and Breast Cancer
RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells.
NCT00875355
·
Paris
Completed
Convection-Enhanced Delivery of 124I-Omburtamab for Patients With Non-Progressive Diffuse Pontine Gliomas Previously Treated With External Beam Radiation Therapy
The purpose of this study is to test the safety of a new method to treat Diffuse Intrinsic Pontine Glioma (DIPG).
NCT01502917
·
New York, New York and 1 other
Completed
Neural Correlates of Language Control in Bilinguals. Functional MRI and Stimulation Mapping Data in Awake Surgery.
For bilingual and multilingual patients, brain activation and Electric Stimulation Mapping studies have shown that different languages may be localized, at least partially, in…
NCT02391493
·
Toulouse
Completed
A Study of Xeloda (Capecitabine) in Breast Cancer Patients With Central Nervous System (CNS) Progression
This single arm study will assess the efficacy of Xeloda in the treatment of brain metastases in breast cancer patients with central nervous system (CNS) progression after whole…
NCT01077726
·
Angers and 11 others
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