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The Effect of Preoperative Walking Exercises on the Prognosis of Supratentorial Brain Tumours Patients After Craniotomy | Clinical Trials | Clareo Health

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The Effect of Preoperative Walking Exercises on the Prognosis of Supratentorial Brain Tumours Patients After Craniotomy

The Role of Short-term Preoperative Walking Exercises in Protecting Cognitive Function and Reducing the Incidence of Surgery-related Complications in the Short Term After Craniotomy in Patients With Supratentorial Brain Tumours

NCT05930288•Xiangya Hospital of Central South University

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to learn about in patients with supratentorial brain tumours. The main questions it aims to answer is: Can short-term preoperative walking exercise protect cognitive function in the short term after craniotomy in patients with supratentorial brain tumor and reduce the incidence of surgery-related complications? Participants will be asked to receive general care and regular walking exercises prior to surgery. Researchers will compare patients who receive only general care before surgery to see if preoperative walking exercise has an effect on postoperative prognosis.

Eligibility

Age

18 - 65 years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•The participants voluntarily joined this trial and signed the informed consent form, and were able to comply with the research procedures.
•Male and female outpatients or inpatients aged between 18 and 65 years.
•Patients diagnosed with supratentorial tumors through medical history, physical examination, laboratory tests, and head imaging examinations, and without symptoms of intracranial hypertension or epilepsy.
•Patients for elective surgery at low risk, as determined by medical experts based on the patient's actual condition and patient's wishes, who are initially expected to wait for more than three to four weeks before surgery, and for whom, it is anticipated that the condition will not progress during the waiting period.

Exclusion Criteria

•The patient with a substantial brain tumor who is significantly susceptible to tumor stroke or brain herniation.
•Patients with a clinical diagnosis of cerebral haemorrhage or intracranial infection or epilepsy.
•Patients with acute or unstable heart disease (e.g. unstable angina or severe aortic stenosis).
•Patients with a physical status of Grade 3, 4 or 5 according to the American Society of Anesthesiologists classification.
•Patients with disabling orthopaedic or neuromuscular conditions.
•Patients with a history of clinically diagnosed cognitive impairment, such as dementia and mental retardation.
•Patients with a current or previous diagnosis of significant mental illness, chronic neurological disease or active substance abuse (as per the Diagnostic and Statistical Manual of Mental Disorders 5th edition).
•Patients with heart failure (New York Heart Association Class 3 or Class 4 functional class).
•Patients with severe chronic obstructive pulmonary disease (exertional expiratory volume in the first second of exhalation \< 50% of predicted value).
•Patients with anaemia (symptomatic or haematocrit \< 30%).
+4 more criteria

Locations (1)

Xiangya Hospital of Central South University

Changsha, Hunan, China

Key Dates

Start Date

March 1, 2024

Primary Completion Date

April 1, 2026

Completion Date

April 1, 2026

Last Updated

January 30, 2024

Enrollment

160

ESTIMATED participants

Conditions

Supratentorial Brain TumorExerciseCognitionPostoperative Complications

Interventions

Walking exercise

BEHAVIORAL

Contacts

Zhixiong Liu, MD

CONTACT

+86-13607318785 zhixiongliu@csu.edu.cn

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: January 30, 2024Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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The Effect of Preoperative Walking Exercises on the Prognosis of Supratentorial Brain Tumours Patients After Craniotomy

Inclusion Criteria

Exclusion Criteria

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