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NCT07438431
Delayed onset muscle soreness (DOMS) is the pain, stiffness, and discomfort that usually appear 24-72 hours after doing an unusual or intense physical activity. Previous studies have shown that both Kinesio taping and the Graston technique can help reduce this type of muscle soreness. However, it is not clear which method is more effective, and their effects on muscle oxygen levels, muscle strength during functional tasks, and reaction time have not been compared directly. The aim of this study was to compare these two treatment methods in people who developed DOMS. A total of 30 healthy participants took part in the study. One group received Kinesio taping, the second group received the Graston technique, and the third group did not receive any treatment and was left to recover naturally. Muscle oxygen levels, functional muscle strength, and reaction times were measured before exercise and again 48 hours later, and the results were compared.
NCT06810271
After completing novel activity or exercise we may experience exercise-induced muscle damage (EIMD), resulting in a period of reduced muscle function and delayed onset muscle soreness (DOMS). DOMS is characterized by muscle pain and tenderness that typically resolves within a week. While the precise cause of DOMS is unknown, there is growing evidence implicating damage to the connective tissue that surrounds our muscle fibers and is related to a small amount of inflammation. This inflammation is a normal part of our body's ability to recovery from injuries and may be visualized through the use of ultrasound technology. A variety of recovery techniques have been proposed that may help with the recovery of DOMS such as massage and electrical muscle stimulation, but these are not always accessible. Therefore, we are interested in investigating whether the number of daily steps can affect how you experience DOMS.
NCT05326893
In the study, 34 healthy sedentary male volunteers were randomly divided into two groups as NM (n = 17) and SHAM-NM (n = 17). After the initial evaluation of the individuals, femoral nerve NM and placebo NM techniques were administered three sets a day with ten repetitions for three days a week for three weeks. Three days after the end of the applications, the second evaluations were made and the DOMS creation protocol for the quadriceps femoris (QF) muscle was initiated. In order to trigger DOMS in individuals, 30 sets and 10 repetitions of eccentric knee extension (35°-95° flexion angles, 30°/sec speed) were performed on the dominant lower extremity with an isokinetic dynamometer. Baseline evaluations were repeated immediately after the DOMS protocol, and at hours 24, 48, and 72. During evaluations, muscle damage (serum creatine kinase (CK), lactate dehydrogenase (LDH), and inflammation (interleukin-6 (IL-6), tumor necrosis factor-alpha) biomarkers, pain (activity), pressure pain threshold, and performance (one-leg jump, vertical jump) parameters were measured.
NCT06535906
Delayed muscle soreness is pain and tenderness that occurs after unusual exercises, most often involving eccentric contraction. This sensitivity, which usually begins in the distal part of the muscle and is intense, spreads progressively throughout the entire muscle 24-48 hours after exercise. The intensity of the discomfort increases within the first 24 hours following cessation of exercise, peaks between 24 and 72 hours, decreases and eventually disappears within 5-7 days after exercise. Delayed onset muscle soreness is considered one of the most common and recurring forms of sports injuries. The most prominent symptoms and findings are a decrease in joint range of motion and strength, edema, stiffness, pain and tenderness. In the planned study, the investigatorss aimed to compare the effects of kinesio taping, manual drainage, placebo kinesio taping and placebo kinesio taping on pain intensity, pain threshold and tolerance, sensory sensitivity and connective tissue stiffness in individuals with delayed-onset muscle soreness.48 healthy adults will be included in our study. Participants will be divided into four groups of 12 people: kinesio taping, placebo kinesio taping, manual lymph drainage and placebo manual lymph drainage. Our participants will have a maximum repetition weight on their wrist flexor muscles, and a delayed muscle soreness protocol will be applied using 80% of this amount. In our participants, pain at rest and activity (VAS), pressure pain threshold and tolerance (algometer), tactile sense (Semmes-Weinstein Monofilament Test), edema (circumference measurement with tape measure), treatment satisfaction and effect (VAS), tissue tension (skin rolling). and perceived fatigue (VAS) will be evaluated. The researchers plan to conduct 5 assessments: before the delayed-onset muscle soreness protocol, immediately after the protocol, immediately after treatment, and 24 hours and 48 hours after the initial assessment.
NCT06612502
The goal of this clinical trial is to learn the effect of percussion massage therapy (PMT) on the recovery of delayed onset muscle soreness (DOMS) in physically active young men. The main question it aims to answer is: Compared with static stretching, Do 25 minutes and 40 minutes of PMT can decrease pain and increase the rang of motion of knee of low limb DOMS in physically active young men? Compared with static stretching, Do 25 minutes and 40 minutes of PMT sessions can increase power and improve the neuromuscular electrophysiology of low limb DOMS in physically active young men? Researchers will compare 25 minutes and 40 minutes of PMT to a static stretching to see if different times of PMT are better to treat DOMS. Participants will: Undergo squats to induce low limb DOMS. Receive static stretching, 25 minutes and 40 minutes of PMT, respectively for three times. Visit the lab for four times in one week for tests.
NCT06225388
Running is the most popular physical activity worldwide. Although running provides many health benefits, it is often associated with injuries and symptoms such as delayed onset muscle soreness. There is still a paucity of interventions that can effectively minimise these symptoms in distance runners.
NCT05607212
The primary purpose of the study is to assess the muscle contractility and sensitivity of lumbar erector spinae, biceps femoris, and gluteus maximus short-term response to Tabata kettlebell swing protocol.
NCT05982665
This study assesses the effect of molecular hydrogen inhalation in healthy males on muscle soreness, fatigue, oxidative stress, and inflammation following eccentric muscle contraction during downhill walking on the treadmill.
NCT06076356
Objective of this study is to compare the effects of foam roller with KT tape on DOMS. The university going students will be divided in two groups, with one group receiving Kinesio Tape as intervention and other Foam Rolling as intervention. Pain and range of motion will be assessed before and after the intervention and the effects of both interventions will be compared.
NCT03698032
Pistachios are an understudied and often unappreciated functional food. While nuts in general have received somewhat more attention for their nutritional properties from researchers, practitioners and the media, pistachios often seem to be overlooked. Meanwhile, pistachios appear to possess characteristics that suggest that they are likely to impart benefits that are equal to and perhaps above and beyond those of average nuts. We intend to explore the potential impacts of pistachios on recovery from rigorous exercise in well-trained athletes. We hypothesize that feeding 1.5 oz of pistachios will improve exercise recovery as determined by a reduction in delayed onset muscle soreness and suppression of markers of muscle damage, inflammation and oxidative stress in comparison to water and that the benefits will be greater with consumption of 3.0 oz of pistachios.
NCT03986242
Delayed-onset muscle soreness (DOMS) is an acute micro-trauma or inflammatory response experienced in the most runners; and, it concurrently impairs athletic performance and may increase the risk of sports injury. Alleviating the symptoms of DOMS strategies are various; however, the specific recovery way remains unconcluded. Furthermore, few studies have investigated the effects of vibrating roller on alleviating the symptoms of DOMS and understand the biochemical changes in response to recovery of athletic performance. Therefore, this study hypothesizes that vibration rolling (VR) could provide a self-myofascial release. Meanwhile, vibration exercise could transmit vibration to specific muscle groups to decrease inflammation in corresponding to reduce muscular pain. Therefore, it could offer positive effects including improvements of flexibility, muscle stiffness, visual analog scale (VAS) for pain, jump, and dynamic balance.
NCT02923102
The aim of the study is to investigate a pre and post workout supplementation (15 days) with Recoverben® , a Aloysia citriodora extract on recovery after exhaustive exercise. Effects will be investigated with 400mg Recoverben® and compared to placebo.
NCT03228992
The study will assess the sensitivity of the Delayed Onset Muscle Soreness Model by comparing the safety and efficacy of oral ibuprofen to placebo over 24 hours.
NCT02339129
This is a Phase 2, prospective, randomized, dual-center, double-blind, placebo-controlled, parallel-group study designed to determine the dosing interval, efficacy and safety of SST-0225 (5.4 grams, applied up to 6 times in 24 hours, over a 48-hour dosing period) for the treatment of pain associated with DOMS.
NCT02271854
This study will assess the analgesic efficacy of DSG 1% compared to placebo in the reduction of the pain associated with DOMS
NCT01921777
To investigate and compare the effects of Traumeel®S tablets versus placebo on recovery and inflammatory immune response over a period of 72 hours after a second bout of strenuous concentric exercise on bicycle (exercise #2).
NCT01781910
The purpose of this study is to determine if a dietary supplement containing branched chain amino acids will reduce the muscle soreness that sometimes occurs in the days following exercise.
NCT00745771
Multiple-dose, double-blind, double-dummy, parallel, randomized, placebo and active controlled study of pharmacokinetics of Diractin® as well as safety and efficacy for muscle soreness from exercise.