Clinical Trials in Tennessee

Showing 12901-12920 of 17,345 trials

Safety and PK Study of CC-90001 in Subjects With Pulmonary Fibrosis

NCT02510937

Participation in the study will last for 3months, with a 1 month screening phase.

Celgene16 participantsStarted Aug 2015

Tampa, Florida, United States • Michigan City, Indiana, United States • Pittsburgh, Pennsylvania, United States +3 more locations

COMPLETEDEARLY Phase 129 miles

Low Dose Aspirin Inhibition of COX-2 Derived PGE2 in Male Smokers

NCT01796951

Regular aspirin use has been associated with a reduction in the development of a number of different malignancies including lung cancer. The mechanism of aspirin's cancer prevention is not known. This study will evaluate whether once daily aspirin use can reduce the production of a protein named prostaglandin E2 (PGE-2), which is known to promote cancer. Specifically, this study will evaluate if aspirin can inhibit the production of PGE-2 by blocking an enzyme named cycloxygenase-2 (COX-2). To accomplish these goals, participants will take either aspirin 325 mg daily, celecoxib 200 mg twice daily, or the combination of both during various days of this 16-day study. Urine be collected to evaluate for PGE-2 production at 4 timepoints in this 16-day study.

Tobacco Use DisorderSmoking

Vanderbilt University6 participantsStarted Feb 2013

Nashville, Tennessee, United States

COMPLETED29 miles

Joint Pain and Medication Adherence in Postmenopausal Women Receiving Aromatase Inhibitors

NCT00954564

RATIONALE: Gathering information over time about joint pain and stiffness from postmenopausal women with early-stage breast cancer who are receiving aromatase inhibitors may help doctors plan treatment and help patients live more comfortably. PURPOSE: This observational epidemiologic cohort is designed to study arthralgia, patient-reported outcomes, and medication adherence in postmenopausal women with early-stage breast cancer who are receiving aromatase inhibitors.

ArthralgiaBreast Cancer

Vanderbilt University Medical Center351 participantsStarted Jun 2009

Nashville, Tennessee, United States • Nashville, Tennessee, United States

Safety and PK Study of CC-90001 in Subjects With Pulmonary Fibrosis

Low Dose Aspirin Inhibition of COX-2 Derived PGE2 in Male Smokers

Joint Pain and Medication Adherence in Postmenopausal Women Receiving Aromatase Inhibitors

Find Trials by Condition in Tennessee

Childhood Cancer Survivors' Knowledge of Diagnosis,Treatment and Risk of Late Effects: Specialized Survivorship Clinic

The Angel® Catheter Pivotal Clinical Trial

Biochemical and Radiological Indicators of Cardiovascular Morbidity in Children With Premature Pubarche

Protein and Phospholipid Analysis of HDL in Patients With Very High Serum Levels of HDL-C

MRI Imaging of Chronobiologic Abnormalities in Depression

Biology in Patients With Reflux Esophagitis

Identification of Inpatients at Risk for Poor Glycemic Control

Safety of Non-delayed Weight Bearing After Total Hip Replacement With Non-Cemented Fiber Metal Taper Stem

Study of Effects of L-Arginine in Colitis and Colon Cancer

An Open Label Study To Assess The Safety And Tolerability Of BEMA® Buprenorphine NX In Opioid Dependent Subjects

Clinical Trial of Peripheral Prism Glasses for Hemianopia

A Research Study of an Investigational Drug ALO-02 (Oxycodone Hydrochloride and Naltrexone Hydrochloride) in Patients With Moderate to Severe Chronic Low Back Pain

Sudden Deafness Treatment Trial

Viral Pathogenesis of Early Cystic Fibrosis Lung Disease

Effects of Carbidopa/Levodopa/Entacapone on Motor Function and Quality of Life in Patients With Parkinson's Disease

Safety Assessment of Two Schedules of Intravenous Infusions of SNS-595 for the Treatment of Hematologic Malignancies

A Safety and Efficacy Study of Tralokinumab in Adults With Asthma