A Blinded Study to Evaluate Effect on Atrial Fibrillation Burden in Patients With Paroxysmal Atrial Fibrillation

Exclusion Criteria

• •Women of childbearing potential
• •AFB \< 3% or \> 70%, during both screening periods independently
• •Permanent or persistent Atrial Fibrillation
• •Cardioversion within 3 months of study drug administration
• •Stroke within 12 months of study drug administration
• •TIA within 12 months of study drug administration
• •Heart failure of NYHA class III or greater (symptoms of heart failure at rest or with minimal exertion)
• •Heart failure of NYHA class II (symptoms of heart failure with routine levels of exertion)with ejection fraction \<40% as measured by echocardiography at any time within 12 months of study enrollment (i.e. additional ejection fraction measurements ≥ 40% over this period will not counter this exclusion)
• •Valvular heart disease (including any valvular insufficiency or stenosis greater than"mild")
• •Ablation within 3 months of study enrollment