Clinical Trials in Tennessee

Showing 10761-10780 of 20,239 trials

Folate Receptor Alpha Peptide Vaccine With GM-CSF in Patients With Triple Negative Breast Cancer

NCT02593227

This Phase II trial evaluates the safety and immunogenicity of two doses of the Folate Receptor Alpha (FRα) peptide vaccine mixed with GM-CSF as a vaccine adjuvant, with or without a immune priming with cyclophosphamide, as a consolidation therapy after neoadjuvant or adjuvant treatment of patients with Stage IIb-III triple negative breast cancer (TNBC).

Breast Cancer

Marker Therapeutics, Inc.80 participantsStarted Apr 2016

Tampa, Florida, United States • Westwood, Kansas, United States • Baltimore, Maryland, United States +8 more locations

COMPLETEDNA29 miles

Plant Based Diet, Ethnicity, and the Gut Microbiome

NCT03314194

Samples will be collected to determine human genetic variation, fecal and oral microbial communities, and metabolome products. Several evolutionary and ecological diversity metrics will be distilled to test: a) if microbiome variation within each ethnicity is less than that between ethnicities; b) if microbiome variation is finely structured according to genetic relatedness; and c) if dietary variation impacts human genome x microbiome associations.

Diet ModificationMicrobial Colonization

Vanderbilt University Medical Center38 participantsStarted Aug 2017

Nashville, Tennessee, United States

Folate Receptor Alpha Peptide Vaccine With GM-CSF in Patients With Triple Negative Breast Cancer

Plant Based Diet, Ethnicity, and the Gut Microbiome

Find Trials by Condition in Tennessee

Efficacy and Safety of LBH589B in Adult Patients With Refractory Chronic Myeloid Leukemia in Accelerated or Blast Phase

Safety, Tolerability, and Efficacy of Monotherapy and Combination Regimens in Participants With Nonalcoholic Steatohepatitis (NASH)

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of ABBV-3373 in Participants With Moderate to Severe Rheumatoid Arthritis (RA)

Safety and Efficacy Study of GRT6005 in Patients With Osteoarthritis (OA) Knee Pain

Dose Response of 28 Days of Dosing of GSK962040 in Type I and II Diabetic Male and Female Subjects With Gastroparesis

LVRC IDE Crossover Study (Crossover From IDE Trial CLN0009)

QPI-1002 Phase 3 for Prevention of Major Adverse Kidney Events (MAKE) in Subjects at High Risk for AKI Following Cardiac Surgery

NeoMend ProGEL™ Pleural Air Leak Sealant Post-Approval Study

Treatment of Chronic Deep Vein Thrombosis (DVT) and Post-Thrombotic Syndrome (PTS) With the EkoSonic® Endovascular System

A Study to Evaluate the Safety and Pharmacology of Subcutaneous Administration of CINRYZE With Recombinant Human Hyaluronidase

A Long Term Study of ALKS 5461 in the Treatment of Refractory Major Depressive Disorder (MDD)

Study to Prevent Acute Kidney Injury After Cardiac Surgery Involving Cardiopulmonary Bypass

Efficacy and Safety Study of Certolizumab Pegol (CZP) Versus Active Comparator and Placebo in Subjects With Plaque Psoriasis (PSO)

Combination Adenovirus + Pembrolizumab to Trigger Immune Virus Effects

Evaluation of Renal Function in Subjects Who Had Undergone Cardiac Surgery

Cebranopadol Efficacy and Safety in Diabetic Patients Suffering From Chronic Pain Caused by Damage to the Nerves

Safety and Efficacy of Cryoablation for the Palliation of Painful Bone Metastases

Safety Study for Beta Thalassemia Subjects on PTG-300