Clinical Trials in Tennessee

Showing 881-900 of 9,675 trials

Randomized Clinical Trial for Ewing Amputation in the VA

NCT05437562

This study follows the Pilot Investigation of Ewing Amputation for Veterans with PAD Undergoing a Below Knee Amputation. The 2 year pilot feasibility phase has concluded recruitment and enrollment. The current phase is a 5 year randomized study of Ewing Below Knee Amputation vs. Standard Below Knee Amputation. If Veterans participate, they will be randomized to either Ewing Amputation or Standard Below Knee Amputation. The scientific premise motivating this proposal is that Ewing Amputation is a promising surgical technique that may improve walking metrics in dysvascular Veterans by providing a better residual limb and improving pain and balance. In preparation of this proposal, we have formed multi-disciplinary surgical teams at each site, and we have been supported by a clinical trial planning meeting to garner the considerable expertise in rehabilitation and amputee assessment from VA and DOD experts to assist in the design of this proposal, testing the overall hypothesis that: Ewing Amputation can help Veterans walk.

Peripheral Arterial Disease

VA Office of Research and Development120 participantsStarted Feb 2026

Decatur, Georgia, United States • Nashville, Tennessee, United States • Houston, Texas, United States

ACTIVE_NOT_RECRUITINGPHASE229 miles

A Study of Abemaciclib (LY2835219) Plus Tamoxifen or Abemaciclib Alone in Women With Metastatic Breast Cancer

NCT02747004

The main purpose of this study is to evaluate the safety and efficacy of abemaciclib plus tamoxifen or abemaciclib alone in women with previously treated hormone receptor-positive (HR+), human epidermal growth factor receptor 2 negative (HER2-), metastatic breast cancer.

Metastatic Breast Cancer

Eli Lilly and Company234 participantsStarted Sep 2016

Tucson, Arizona, United States • Lebanon, New Hampshire, United States • Nashville, Tennessee, United States +56 more locations

Randomized Clinical Trial for Ewing Amputation in the VA

A Study of Abemaciclib (LY2835219) Plus Tamoxifen or Abemaciclib Alone in Women With Metastatic Breast Cancer

Find Trials by Condition in Tennessee

A Longitudinal Observational Study of the Natural History and Management of Patients With HCC

Suppression of Ovarian Function With Either Tamoxifen or Exemestane Compared With Tamoxifen Alone in Treating Premenopausal Women With Hormone-Responsive Breast Cancer

A Study of TAK-188 in Adults With Advanced or Spreading Solid Tumors

Registry of the Patient Experience for Carpal Tunnel Release

A Study to Learn About the Study Medicine Called PF-07258669 in Older Adults Including Those at Risk of Malnutrition

A Research Study to See How Well CagriSema Compared to Tirzepatide Helps People With Obesity Lose Weight

Study of First-line Pembrolizumab (MK-3475) With Lenvatinib (MK-7902/E7080) in Urothelial Carcinoma Cisplatin-ineligible Participants Whose Tumors Express Programmed Cell Death-Ligand 1 and in Participants Ineligible for Platinum-containing Chemotherapy (MK-7902-011/E7080-G000-317/ LEAP-011)

Evaluation of a Non-Implanted Electrical Stimulation Device for Overactive Bladder (OAB)

A Study to Learn About the Study Medicine Called PF-07976016 in Adults With Obesity

Endovascular AAA Intervention Using the GORE® EXCLUDER® Conformable AAA Endoprosthesis or Iliac Branch Endoprosthesis

Study of Efficacy and Safety of Investigational Treatments in Patients With Moderate to Severe Hidradenitis Suppurativa

DB-1311 in Combination With BNT327 or DB-1305 in Advanced/Metastatic Solid Tumors

CLOZAPINE Response in Biotype-1

A Study to Evaluate the Safety and Effectiveness of the Rapidlink Device When Used in Patients Undergoing an Open Surgical Procedure to Repair the Aorta

Pertuzumab, Trastuzumab, Hyaluronidase-zzxf and Enzalutamide for Treatment of Metastatic Castration-Resistant Prostate Cancer

A Study of MGC026 in Participants With Advanced Solid Tumors

Study of HRO761 Alone or in Combination in Cancer Patients With Specific DNA Alterations Called Microsatellite Instability or Mismatch Repair Deficiency.

Study of ARO-ATXN2 Injection in Adults With Spinocerebellar Ataxia Type 2