Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Bristol-Myers Squibb
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Diagnosis of B-CLL by NCI criteria
Require chemotherapy and have fully recovered from previous administered chemotherapy
Subjects must have progressed, failed to achieve a meaningful response, or relapsed/intolerant to prior therapy. Failing at least one purine analogue regimen
Subjects have received three or fewer prior treatment regimens
ECOG status of 0 - 2
If dose level + 3 is reached, the criteria is the same as outlined for Cohort #1, however the subjects should not have a history of prior chemotherapy (treatment naive)
You may not be if
Unwilling or unable to use an acceptable method to avoid pregnancy
Uncontrolled or significant cardiovascular disease, including prolonged QTc interval
History of significant bleeding disorder, unrelated to CLL
Prior concurrent malignancy
Drugs that generally accepted to have the risk of causing Torsades de Pointes
Autoimmune hemolytic anemia requiring therapy or transfusion support
Autoimmune thrombocytopenia requiring steroid therapy or transfusion support
