Clinical Trials in Tennessee

Showing 4001-4020 of 20,239 trials

Safety and Proof-of-Concept (POC) Study With AMT-130 in Adults With Early Manifest Huntington's Disease

NCT04120493

This is the first study of AMT-130 in patients with early manifest HD and is designed to establish safety and proof-of-concept (PoC). CT-AMT-130-01 is a Phase 1/2, multicenter, first-in-human (FIH) study. The first three cohorts of the study have completed enrollment, including the randomized, double-blind, sham-controlled cohorts. Cohort 4 is open-label. Cohort 4 participants will receive high dose AMT-130.

Huntington's Disease

UniQure Biopharma B.V.43 participantsStarted Sep 2019

Birmingham, Alabama, United States • Tucson, Arizona, United States • San Francisco, California, United States +9 more locations

TERMINATEDPhase 129 miles

A Study of ZW171 in Participants With Advanced or Metastatic Mesothelin-expressing Cancers

NCT06523803

This study is being done to find out if ZW171 is safe and can treat participants with advanced (locally advanced \[inoperable\] and/or metastatic) mesothelin-expressing cancers.

Mesothelin-expressing Advanced Cancers

Zymeworks BC Inc.32 participantsStarted Sep 2024

Los Angeles, California, United States • Aurora, Colorado, United States • Louisville, Kentucky, United States +12 more locations

Safety and Proof-of-Concept (POC) Study With AMT-130 in Adults With Early Manifest Huntington's Disease

A Study of ZW171 in Participants With Advanced or Metastatic Mesothelin-expressing Cancers

Find Trials by Condition in Tennessee

First-in-human Study of DS-1062a for Advanced Solid Tumors (TROPION-PanTumor01)

A Study of bbT369 in Relapsed and/or Refractory B Cell Non-Hodgkin's Lymphoma (NHL)

Trial of Indication-Based Transfusion of Red Blood Cells in ECMO

Stress and Opioid Misuse Risk: The Role of Endogenous Opioid and Endocannabinoid Mechanisms

PRV-015 in Gluten-free Diet Non-responsive Celiac Disease

To Evaluate Efficacy and Safety of Serplulimab + Chemotherapy (Carboplatin- Etoposide) in US Patients With ES-SCLC

A Phase 2 Study to Evaluate the Safety, Tolerability, and Immune Response of AFX3772 Vaccine in Healthy Infants

GRAVITAS-119: Itacitinib in Combination With Calcineurin Inhibitor-Based Interventions for the Prophylaxis of Graft-Versus Host Disease

Medtronic Transcatheter Aortic Valve Replacement (TAVR) Low Risk Bicuspid Study

Open-label Long-term Study of Adjunctive Brivaracetam in Pediatric Subjects With Epilepsy

Study of Daxdilimab (HZN-7734) in Participants With Moderate-to-Severe Primary Discoid Lupus Erythematosus

Nonhealing Diabetic Foot Ulcers Treated With Standard of Care (SOC) Alone or Standard of Care and Amnion-Intermediate-Chorion (AIC)

Hearing Impairment, Strategies and Outcomes in VA Emergency Departments

A Prospective Registry to Enable Collection of Standardized Routine Care Oncology Patient Data

Ultrasound-Guided Percutaneous Cryoneurolysis to Treat Postoperative Pain After Mastectomy

Prospective Healthcare-Associated Links in Transmission of Nontuberculous Mycobacteria

Artacent Amniotic Tissue for Treatment of Chronic Lower Extremity Diabetic Ulcers.

Study of VIR-2218, VIR-3434, and/or PEG-IFNα in Subjects With Chronic Hepatitis B Virus Infection