Clinical Trials in Seattle

Showing 3501-3520 of 4,491 trials

Tocilizumab for Chronic Graft-versus-Host Disease Treatment

NCT02174263

This phase II trial studies how well tocilizumab works in treating chronic graft-versus-host disease (GVHD) in patients that have not responded to treatment after at least two prior therapies. Tocilizumab blocks a protein that stimulates the body's immune system. By blocking this protein, the investigators may reduce the symptoms of chronic GVHD.

Graft Versus Host Disease

Fred Hutchinson Cancer CenterStarted Feb 2016

Phoenix, Arizona, United States • Rochester, Minnesota, United States • Nashville, Tennessee, United States +2 more locations

TERMINATEDPhase 2< 1 mile

LDE225 for Patients With PTCH1 or SMO Mutated Tumors

NCT02002689

The purpose of this signal seeking study is to determine whether treatment with LDE225 demonstrates sufficient efficacy in hedgehog pathway-mutated solid tumors and/or hematologic malignancies to warrant further study

PTCH1 or SMO Activated Solid and Hematologic Tumors

Novartis Pharmaceuticals10 participantsStarted Feb 2014

Sacramento, California, United States • Greenwood Village, Colorado, United States • Chicago, Illinois, United States +7 more locations

Tocilizumab for Chronic Graft-versus-Host Disease Treatment

LDE225 for Patients With PTCH1 or SMO Mutated Tumors

Find Trials by Condition in Seattle

An Efficacy and Safety Study of Golimumab (CNTO 148) in Participants With Moderately to Severely Active Ulcerative Colitis

CLE for Assessment of Neoplasia After Mucosal Ablation or Resection of Gastrointestinal Neoplasia

Comparative Effectiveness of Adding Weight Control to Smoking Cessation Quitlines

A Safety Study for Cethrin (BA-210) in the Treatment of Acute Thoracic and Cervical Spinal Cord Injuries

Diffusion Weighted Imaging Evaluation for Understanding Stroke Evolution Study-2 (DEFUSE-2)

Early Versus Delayed Enteral Feeding and Omega-3 Fatty Acid/Antioxidant Supplementation for Treating People With Acute Lung Injury or Acute Respiratory Distress Syndrome (The EDEN-Omega Study)

Pharmacokinetic and Pharmacodynamic Study of IDN-6556 in ACLF

Niacin Plus Statin to Prevent Vascular Events

Study of Ivacaftor in Cystic Fibrosis Subjects 2 Through 5 Years of Age With a CFTR Gating Mutation

Rabeprazole Extended-Release 50 mg Versus Esomeprazole 40 mg for Healing and Symptomatic Relief of Mild to Moderate Erosive Gastroesophageal Reflux Disease (GERD)

Effect of Otamixaban Versus Unfractionated Heparin + Eptifibatide in Patients With Unstable Angina/Non ST Elevation Myocardial Infarction Undergoing Early Invasive Strategy

A Study of BIND-014 (Docetaxel Nanoparticles for Injectable Suspension) as Second-line Therapy for Patients With KRAS Positive or Squamous Cell Non-Small Cell Lung Cancer

Effectiveness of a Wheelchair Skills Training Program for Power Mobility Users: A Randomized Controlled Trial

Study of the Safety and Clinical Effects of 2 Doses of EVP-6124 in Subjects With Alzheimer's Disease Who Complete Study EVP-6124-024 or EVP-6124-025

Inhaled Mannitol as a Mucoactive Therapy for Bronchiectasis

Safety and Immunogenicity of A/H1N1-SOIV (Swine Flu) Vaccine With and Without Adjuvant in Children (3 to < 9 Years)

ADAGIO Follow Up Study: Evaluation of the Long-Term Effects of Rasagiline in Parkinson's Disease Subjects

Zomig - Treatment of Acute Migraine Headache in Adolescents