Clinical Trials in Seattle

Showing 321-340 of 9,312 trials

SOUND Pivotal Trial - (Sonomotion stOne comminUtion resoNance ultrasounD)

NCT05701098

The goal of this clinical trial is to test the Break Wave™ system in patients with upper urinary tract stones. The main question it aims to answer is whether the device is safe and effective in fragmenting (breaking) stones. Participants will a) undergo the Break Wave™ procedure, b) have a telehealth visit at 2 weeks, and c) return for an imaging study at approximately 10 weeks post-procedure.

Kidney StoneUrolithiasisNephrolithiasis+4 more

SonoMotion64 participantsStarted Oct 2023

San Diego, California, United States • San Francisco, California, United States • Santa Clara, California, United States +7 more locations

Active Not RecruitingPhase 2< 1 mile

A Study Testing the Effect of Immunotherapy (Ipilimumab and Nivolumab) in Patients With Recurrent Glioma With Elevated Mutational Burden

NCT04145115

This phase II trial studies the effect of immunotherapy drugs (ipilimumab and nivolumab) in treating patients with glioma that has come back (recurrent) and carries a high number of mutations (mutational burden). Cancer is caused by changes (mutations) to genes that control the way cells function. Tumors with high number of mutations may respond well to immunotherapy. Immunotherapy with monoclonal antibodies such as ipilimumab and nivolumab may help the body's immune system attack the cancer and may interfere with the ability of tumor cells to grow and spread. Giving ipilimumab and nivolumab may lower the chance of recurrent glioblastoma with high number of mutations from growing or spreading compared to usual care (surgery or chemotherapy).

Astrocytoma, IDH-Mutant, Grade 4Diffuse GliomaGlioblastoma, IDH-Wildtype+1 more

National Cancer Institute (NCI)37 participantsStarted Dec 2020

Anchorage, Alaska, United States • Anchorage, Alaska, United States • Anchorage, Alaska, United States +413 more locations

SOUND Pivotal Trial - (Sonomotion stOne comminUtion resoNance ultrasounD)

A Study Testing the Effect of Immunotherapy (Ipilimumab and Nivolumab) in Patients With Recurrent Glioma With Elevated Mutational Burden

Find Trials by Condition in Seattle

Benefits of Outdoor Walks in Reducing Depressive Symptoms

Combination Chemotherapy With or Without Temsirolimus in Treating Patients With Intermediate Risk Rhabdomyosarcoma

Saroglitazar Magnesium for Treatment of Primary Biliary Cholangitis

A Study Evaluating Efruxifermin in Subjects With Non-invasively Diagnosed Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Nonalcoholic Fatty Liver Disease (NAFLD)/Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)

Capivasertib+Fulvestrant vs Placebo+Fulvestrant as Treatment for Locally Advanced (Inoperable) or Metastatic HR+/HER2- Breast Cancer

Augmented Wide Area Circumferential Catheter Ablation for Reduction of Atrial Fibrillation Recurrence

Effect of SPG Block for Patients With Anxiety at Electronic Dance Music Festivals

An Extension Study of Subjects Who Received an Avalyn Inhaled Antifibrotic Agent (SAIL)

A Study of mRNA-1283 Injection Compared With mRNA-1273 Injection in Participants ≥12 Years of Age to Prevent COVID-19

Study to Compare AMG 510 "Proposed INN Sotorasib" With Docetaxel in Non Small Cell Lung Cancer (NSCLC) (CodeBreak 200).

A Study to Assess the Effectiveness and Safety of IPN10200 Over Time in Adults With Moderate to Severe Wrinkle-like Lines Between the Eyebrows

Study of Efficacy and Safety of Iptacopan in Participants With IC-MPGN

Efficacy and Safety of Seralutinib in Adult Subjects With PAH (PROSERA)

A Study to Investigate the Efficacy and Safety of Verekitug (UPB-101) in Adult Participants With Severe Asthma (VALIANT)

A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)

A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate-To-Severe Asthma

ADH1 and ADH2 Disease Monitoring Study (DMS)

A 3-part Study of SYX-5219 in Healthy Volunteers and Participants With Atopic Dermatitis