Renal artery anatomy ineligible for treatment

Secondary hypertension not including sleep apnea

Type I diabetes mellitus or uncontrolled Type II diabetes (defined as plasma HbA1c ≥9.0%)

eGFR \<40

Brachial circumference ≥42 cm

Any history of cerebrovascular event or severe cardiovascular event within 3 months prior to consent

Documented repeat (\>1) hospitalization for hypertensive crisis within 3 months prior to consent

Documented confirmed episode(s) of unstable angina within 3 months prior to consent

Chronic oxygen support or mechanical ventilation other than nocturnal respiratory support for sleep apnea

Primary pulmonary hypertension

Night shift workers

Pregnant, nursing or planning to become pregnant

RADIANCE Continued Access Protocol