Clinical Trials in San Francisco

Showing 901-920 of 6,211 trials

Evaluation of A Clinical Diagnostic Test for CRDS

NCT06188689

Calcium Release Deficiency Syndrome (CRDS) is a novel inherited arrhythmia syndrome secondary to RyR2 loss-of-function that confers a risk of sudden cardiac death. Diagnosis of CRDS presently requires cellular-based in vitro confirmation that an RyR2 variant causes loss-of-function. We hypothesize that CRDS can be diagnosed clinically through evaluation of the repolarization response to brief tachycardia, mediated by cardiac pacing, and a subsequent pause.

Calcium Release Deficiency Syndrome (CRDS)

Population Health Research Institute400 participantsStarted Feb 2023

San Francisco, California, United States • Rochester, Minnesota, United States • Seattle, Washington, United States +15 more locations

RECRUITINGPHASE3< 1 mile

Extension Study to Evaluate Safety and Tolerability of Oral Dersimelagon (MT-7117) in Subjects With Erythropoietic Protoporphyria (EPP) or X-Linked Protoporphyria (XLP)

NCT05005975

To evaluate the long-term safety and tolerability of oral dersimelagon.

EPPXLP

Tanabe Pharma America, Inc.301 participantsStarted Aug 2021

Huntington Beach, California, United States • San Francisco, California, United States • Miami, Florida, United States +48 more locations

Evaluation of A Clinical Diagnostic Test for CRDS

Extension Study to Evaluate Safety and Tolerability of Oral Dersimelagon (MT-7117) in Subjects With Erythropoietic Protoporphyria (EPP) or X-Linked Protoporphyria (XLP)

Find Trials by Condition in San Francisco

Zanzalintinib in Combination With Paclitaxel in Recurrent High Grade Uterine Cancer

Study of Cabozantinib in Combination With Atezolizumab Versus Sorafenib in Participants With Advanced Hepatocellular Carcinoma (HCC) Who Have Not Received Previous Systemic Anticancer Therapy

Matrion Decellularized Placental Membrane Versus Conventional Wound Management in Subjects With Diabetic Foot Ulcers

A Study of Alisertib in Combination With Endocrine Therapy in Patients With HR-positive, HER2-negative Recurrent or Metastatic Breast Cancer

Anal High-risk HPV, HSIL, and Microbiome Among Hispanic Peoples Living With HIV (PLWH)

Evaluation of BE1116 in Patients With Traumatic Injury and Acute Major Bleeding to Improve Survival ( TAP Study )

Treatment of Moderate to Severe Refractory Crohn's Disease

Study of Lifileucel (LN-144), Autologous Tumor Infiltrating Lymphocytes, in the Treatment of Patients With Metastatic Melanoma

A Study of Inebilizumab Efficacy and Safety in IgG4- Related Disease

MAGE A10ᶜ⁷⁹⁶T for Advanced NSCLC

Continuous Infusions vs Scheduled Bolus Infusions

ACP-196 (Acalabrutinib) in Combination With Pembrolizumab, for Treatment of Hematologic Malignancies

A Study to Assess the Safety, Tolerability, and Efficacy of Rocatinlimab in Adolescent Participants With Moderate-to-severe Atopic Dermatitis (AD)

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of IgPro20 in Adults With Dermatomyositis (DM)

An Adaptive Phase 2a/2b Study of LY3871801 in Adult Participants With Rheumatoid Arthritis

A Dose-finding Study to Evaluate the Effect of a Contraceptive Vaginal Ring, Releasing Nestorone® and Estradiol, on Cycle Control, Ovulation Inhibition, and Pharmacokinetics in Normal Cycling Women

An Open-label Extension Trial of CVL-865 as Adjunctive Therapy in the Treatment of Focal Onset Seizures

The PharmFIT Study