A Double-Blind Randomized Clinical Trial of a Rifabutin Regimen in the Treatment of Mycobacterium-Avium Complex (MAC) Bacteremia in Patients With AIDS

Inclusion Criteria

• •Concurrent Medication:
• •Allowed:
• •Zidovudine (AZT).
• •Didanosine (ddI).
• •Patients must have the following:
• •Diagnosis of AIDS as defined by the CDC.
• •Blood cultures positive for Mycobacterium avium complex or for acid-fast bacilli (AFB).
• •Provide written informed consent.
• •Prior Medication:
• •Allowed:
• •If receiving zidovudine (AZT) or ddI must be taking the medication for at least 4 weeks prior to study entry.
• •Required:
• •Antipneumocystis prophylactic therapy for at least 4 weeks prior to study entry.