Clinical Trials in San Francisco

Showing 6301-6320 of 9,883 trials

Study of MLN8237 in Combination With Irinotecan and Temozolomide

NCT01601535

The goal of the first part of this clinical trial (Phase I portion) is to study the side effects, drug breakdown (pharmacokinetics), and dosing of the drug MLN8237 when added to standard chemotherapy drugs, irinotecan and temozolomide. The goal of the second part of this clinical trial (Phase II portion) is to learn how many children and young adults show improvements in their neuroblastoma when treated with the combination of MLN8237, irinotecan, and temozolomide.

Neuroblastoma

New Approaches to Neuroblastoma Therapy Consortium54 participantsStarted May 2012

Los Angeles, California, United States • Palo Alto, California, United States • San Francisco, California, United States +10 more locations

TERMINATEDPhase 2< 1 mile

Prevention of S. Aureus Pneumonia Study in Mechanically Ventilated Subjects Who Are Heavily Colonized With S. Aureus.

NCT02940626

The purpose of this study is the prevention of Staphylococcus aureus pneumonia in mechanically ventilated subjects heavily colonized with S. aureus. Staphylococcus aureus is a human pathogenic bacterium that causes severe infections, including pneumonia and sepsis. Hospital-acquired bacterial pneumonia (HABP) caused by S. aureus, including ventilator-associated bacterial pneumonia (VABP) in mechanically ventilated subjects, is a significant public health threat despite efforts to optimize antibiotic treatment. ASN100 is an investigational monoclonal antibody product that targets the toxins produced by S. aureus to protect subjects from developing S. aureus pneumonia.

Pneumonia, Ventilator-associatedPneumonia, Staphylococcal

Arsanis, Inc.155 participantsStarted Nov 2016

Phoenix, Arizona, United States • Sacramento, California, United States • San Francisco, California, United States +90 more locations

Study of MLN8237 in Combination With Irinotecan and Temozolomide

Prevention of S. Aureus Pneumonia Study in Mechanically Ventilated Subjects Who Are Heavily Colonized With S. Aureus.

Find Trials by Condition in San Francisco

Controlling Urgency Through Relaxation Exercises

Preparing Older Veterans With Serious and Chronic Illness for Decision Making

Temsirolimus With or Without Megestrol Acetate and Tamoxifen Citrate in Treating Patients With Advanced, Persistent, or Recurrent Endometrial Cancer

An Open-label, Phase 1 Study to Determine the Maximum Tolerated Dose of HLX07,in Patients With Advanced Solid Cancers

A Controlled Clinical Study of Dupilumab in Patients With Bilateral Nasal Polyps

Study to Compare PT007 to Placebo MDI and Open-Label Proventil® HFA in Adult and Adolescent Subjects With Asthma

An Extension Study to Assess Vamorolone in Boys With Duchenne Muscular Dystrophy (DMD)

Safety and Efficacy of Relamorelin Administered to Participants With Vomiting Symptoms and Moderate to Severe Diabetic Gastroparesis

Assessment of the Safety, Efficacy, PK, and Extrapulmonary Pharmacodynamics (PD) of Albuterol Sulfate Pressurized Inhalation Suspension (Hereafter Referred to as AS MDI) Compared to Proventil as an Active Control in Subjects With Asthma

A Study to Evaluate BMS-986036 in Obese Adults With Type-2 Diabetes

A Randomized Phase IIa Efficacy and Safety Study of Radium-223 Dichloride With Abiraterone Acetate or Enzalutamide in Metastatic Castration-resistant Prostate Cancer (CRPC)

Trial To Assess The Safety And Tolerability Of Lucinactant For Inhalation In Preterm Neonates 26 to 28 Weeks PMA

Efficacy and Safety Study of SPL7013 Gel to Prevent the Recurrence of Bacterial Vaginosis (BV)

Alisertib in Treating Patients With Recurrent or Persistent Leiomyosarcoma of the Uterus

Extension in AS: Sustainability of Benefits, Safety and Tolerability

Evaluation of the PillCam™ Colon Capsule Endoscopy (PCCE) in the Visualization of the Colon

Different Therapies in Treating Infants With Newly Diagnosed Acute Leukemia

Expanded Treatment Protocol (ETP) of Ruxolitinib in Patients With Polycythemia Vera Who Were Hydroxyurea Resistant or Intolerant and for Whom no Treatment Alternatives Was Available.