Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
vTv Therapeutics
Age
50–85
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Diagnosis of probable Alzheimer Disease (AD) with documented evidence of progression of disease
Mini Mental State Examination (MMSE) score of 21-26, inclusive
Clinical Dementia Rating global score of 0.5 or 1
Alzheimer's Disease Assessment Scale - Cognitive Subscale (ADAS-cog14) of 10 or more
Brain magnetic resonance imaging (MRI) consistent with the diagnosis of probable AD
Concurrent use of cholinesterase inhibitor or memantine with stable dose for at least 2 months prior to screening
Hemoglobin A1c (HbA1c) 6.5% - 9.5%, inclusive
Caregiver willing to participate and be able to attend clinic visits with patient
Ability to ingest oral medications
You may not be if
Significant neurological or psychiatric disease other than Alzheimer's disease
Previous clinical trial participation within 90 days of screening
Previous exposure to putative disease modifying therapy for Alzheimer's disease within 1 year of screening
History of cancer within the last 5 years except adequately treated cervical carcinoma in-situ, cutaneous basal cell or squamous cell cancer, or non-progressive prostate cancer not requiring current treatment
