Study of Azeliragon in Patients With Mild Alzheimer's Disease and Impaired Glucose Tolerance

Exclusion Criteria

• •Significant neurological or psychiatric disease other than Alzheimer's disease
• •Previous clinical trial participation within 90 days of screening
• •Previous exposure to putative disease modifying therapy for Alzheimer's disease within 1 year of screening
• •History of cancer within the last 5 years except adequately treated cervical carcinoma in-situ, cutaneous basal cell or squamous cell cancer, or non-progressive prostate cancer not requiring current treatment
• •Women of childbearing potential
• •Uncontrolled blood pressure and/or blood pressure above 140/90
• •Participants receiving medications that may negatively impact cognitive function
• •History of diabetic ketoacidosis within the past year
• •History of chronic pancreatitis
• •Stage 4 kidney disease
• •Use of insulin therapy