Clinical Trials in San Francisco

Showing 5981-6000 of 9,883 trials

COMPLETEDPhase 1< 1 mile

Safety Study of AADC Gene Therapy (VY-AADC01) for Parkinson's Disease

NCT01973543

Safety study of AADC gene transfer (VY-AADC01) in subjects with Parkinson's disease.

Parkinson's Disease

Neurocrine Biosciences15 participantsStarted Oct 2013

San Francisco, California, United States • Pittsburgh, Pennsylvania, United States

COMPLETEDNA< 1 mile

Pilot Study on the Tolerability of Dietary Dried Plum

NCT01035372

Dried plums (Prunus domestica L.) have traditionally been recognized for their health benefits related to conditions such as constipation, irregular menstrual cycles and mouth sores. This dried fruit provides high levels of fiber, vitamins and minerals. Dried plum has also been shown in animal studies to have beneficial effects on bone and can prevent the loss of bone caused by low hormone levels such as occurs after surgical removal of the ovaries. We also have shown that dried plum can prevent the loss of bone associated with aging in mice. Very few therapies for osteoporosis actually reverse bone loss and improve bone strength. The potential therapeutic value of dried plum in men and women with hormone deficiency or age-related osteoporosis is clear.

HealthyElderly

University of California, San Francisco6 participantsStarted Dec 2009

San Francisco, California, United States

COMPLETEDPhase 2< 1 mile

Safety and Efficacy of Ledipasvir/Sofosbuvir Fixed Dose Combination +/- Ribavirin in Adolescents and Children With Chronic HCV-Infection

NCT02249182

The primary objective of the PK Lead-in Phase of the study is to evaluate the steady state pharmacokinetics (PK) and confirm the dose of ledipasvir/sofosbuvir (LDV/SOF) fixed dose combination (FDC) in hepatitis C virus (HCV)-infected pediatric participants. The PK Lead-in Phase will also evaluate the safety, tolerability, and antiviral activity of 10 days of dosing of LDV/SOF FDC in HCV-infected pediatric participants. The Treatment Phase will be initiated by age cohort after confirmation of age-appropriate LDV/SOF FDC dosage levels. Participants from the PK Lead-in Phase will immediately rollover into the Treatment Phase with no interruption of study drug administration. The primary objective of the Treatment Phase is to evaluate the antiviral efficacy, safety, and tolerability of LDV/SOF FDC +/- ribavirin (RBV) for 12 or 24 weeks in pediatric participants with HCV. During screening, participants will receive placebo to match LDV/SOF FDC to assess ability to swallow tablets.

Hepatitis C Virus Infection

Gilead Sciences226 participantsStarted Nov 2014

Birmingham, Alabama, United States • Los Angeles, California, United States • San Francisco, California, United States +28 more locations

Safety Study of AADC Gene Therapy (VY-AADC01) for Parkinson's Disease

Pilot Study on the Tolerability of Dietary Dried Plum

Safety and Efficacy of Ledipasvir/Sofosbuvir Fixed Dose Combination +/- Ribavirin in Adolescents and Children With Chronic HCV-Infection

Find Trials by Condition in San Francisco

Open-label Safety Study of E/C/F/TAF (Genvoya®) in HIV-1 Positive Patients With Mild to Moderate Renal Impairment

STX-100 in Patients With Idiopathic Pulmonary Fibrosis (IPF)

Paleolithic Diets vs T2D and Improvements in the Metabolic Syndrome

Multi-Center, Randomized, Open-Label Study of G/P +/- RBV for NS5A + SOF Previously Treated GT1 HCV Subjects

The Blood Pressure and Metabolic Effects of Nebivolol in Hypertensive Patients With Impaired Glucose Tolerance or Impaired Fasting Glucose

A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of VX-661/Ivacaftor in Pediatric Subjects With Cystic Fibrosis (CF)

Post Traumatic Stress Disorder (PTSD), Sleep Disordered Breathing And Genetics: Effects On Cognition

Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) and Short Laryngologic Surgery

Study Assessing PTI-428 Safety, Tolerability, Pharmacokinetics and Effect in Subjects With Cystic Fibrosis

T.E.A.M. Feasibility and Efficacy Study 2.0

Evaluate ALLN-177 in Patients With Enteric Hyperoxaluria

A Study to Evaluate Tolerability and Participants Preference Between Mirabegron and Tolterodine Extended Release (ER) in Participants With Overactive Bladder (OAB)

Intrathecal Mafosfamide

Telerehabilitation in the Home Versus Therapy In-Clinic for Patients With Stroke

Study Testing Radium-223 Dichloride in Relapsed Multiple Myeloma

Liposomal Amikacin for Inhalation (LAI) in the Treatment of Mycobacterium Abscessus Lung Disease

A Study to Evaluate Gluten Challenge on Immune Responses in Subjects With Celiac Disease