Clinical Trials in San Francisco

Showing 4901-4920 of 9,883 trials

Epidemiology and Pathogenesis of HIV-Associated Pulmonary Hypertension

NCT00845013

The purpose of this study is to describe the epidemiology of pulmonary hypertension in individuals with HIV infection and to investigate its pathogenesis. We propose to conduct a prospective observational cohort study to determine the association between highly active antiretroviral therapy (HAART) and viral suppression in HIV-infected patients who have been identified to have pre-clinical pulmonary hypertension (Aim 1). In addition, we will investigate the mechanistic role of the HIV-1 Nef protein and HHV-8 infection in the development and progression of pulmonary hypertension in individuals with HIV (Aim 2). We will also investigate endothelial function in HIV-infected patients with pulmonary hypertension (Aim 3).

HIV InfectionPulmonary HypertensionEndothelial Function+1 more

University of California, San Francisco365 participantsStarted Nov 2007

San Francisco, California, United States

COMPLETEDPhase 3< 1 mile

Registrational Study With Omecamtiv Mecarbil (AMG 423) to Treat Chronic Heart Failure With Reduced Ejection Fraction

NCT02929329

The purpose of this study is to determine if treatment with omecamtiv mecarbil when added to standard of care is well tolerated and superior to placebo in reducing the risk of cardiovascular death or heart failure events in adults with chronic heart failure with reduced ejection fraction (HFrEF).

Heart Failure

Cytokinetics8,256 participantsStarted Jan 2017

Birmingham, Alabama, United States • Birmingham, Alabama, United States • Birmingham, Alabama, United States +1030 more locations

Epidemiology and Pathogenesis of HIV-Associated Pulmonary Hypertension

Registrational Study With Omecamtiv Mecarbil (AMG 423) to Treat Chronic Heart Failure With Reduced Ejection Fraction

Find Trials by Condition in San Francisco

Safety of and Immune Response to an H1N1 Influenza Vaccine in HIV Infected Pregnant Women

The Effects of Omega-3 Fatty Acids Supplementation on Endothelial Function and Inflammation

Addressing Involuntary Movements in Tardive Dyskinesia

Study of Reslizumab in Participants With Uncontrolled Asthma and Elevated Blood Eosinophils

A Study to Evaluate the Efficacy and Safety of TEV-48125 (Fremanezumab) for the Prevention of Episodic Cluster Headache (ECH)

A Study Comparing the Efficacy and Safety of Fremanezumab (TEV-48125) for the Prevention of Chronic Cluster Headache (CCH)

A Phase 2, Multicenter, Randomized, Double-Blind, Vehicle Controlled, Parallel-Group, Clinical Study in the Treatment of Acne Vulgaris

A Safety and Efficacy Study of Beclomethasone Dipropionate Delivered Via Breath-Actuated Inhaler (BAI) or Metered-Dose Inhaler (MDI) in Participants Ages 4-11 Years Old With Persistent Asthma

Efficacy and Safety Study of FP MDPI Compared With FS MDPI in Adolescent and Adult Patients With Persistent Asthma

A Study to Evaluate the Safety and Efficacy of Topically Applied TV 45070 Ointment in Patients With Postherpetic Neuralgia (PHN)

An Efficacy and Safety Profile of Inhaled TV48108 in Healthy Volunteers and COPD Patients

A Multiple Dose, Dose Escalation Trial of AEB1102 in Patients With Advanced Solid Tumors

Study of ProMetic BioTherapeutics Immune Globulin Intravenous (Human) 10%

A Study to Evaluate the Efficacy and Safety of DR-102 for the Prevention of Pregnancy

Evaluating the Safety, Tolerability, and Effect of a Human Monoclonal Antibody (VRC01) on Markers of HIV Persistence in HIV-Infected Adults Receiving Antiretroviral Therapy (ART)

Phase 4 Study in Adult Subjects Undergoing Posterior Lumbar Spine Surgeries

Study Assessing the Feasibility of a Surgery and Chemotherapy-Only in Children With Wnt Positive Medulloblastoma

A Study to Test if TEV-50717 is Effective in Relieving Tics Associated With Tourette Syndrome (TS)