Clinical Trials in San Diego

Showing 7781-7800 of 14,679 trials

Care4Today v2.0 Application for Improving Adherence to HIV Medications

NCT02001064

Although poor antiretroviral (ART) adherence in HIV does not mean a complete lack of therapeutic results, the benefit of ART increases as adherence improves. Consequences of suboptimal ART adherence are viral rebound, development of drug-resistant HIV strains, and more rapid progression to AIDS. Moreover, HIV-infected persons tend to have numerous co-occurring conditions and therefore take many medications making adherence to multiple drug regimens more difficult. A mobile application capable of improving medication adherence among HIV-infected persons would be highly useful. The investigators propose an intervention study designed to address these potential mechanisms of nonadherence by utilizing the Care4Today v2.0 smartphone application (app). The current study is a small pilot Randomized Controlled Trial (RCT) comparing the smart phone application titled "Care4Today v2.0" versus standard of care to improve medication adherence to ART over a 4-week period with 60 HIV-infected participants. The pilot RCT consists of 60 HIV-infected persons who are at risk for ART medication nonadherence. Using random assignment, 30 HIV-infected participants will be assigned to medication adherence improvement via "Care4Today" app as compared to 30 HIV-infected participants assigned standard of care. The investigators will assess the effectiveness and acceptability of the app in improving objectively measured ART adherence (i.e., via medication event monitoring system caps) over a 4-week period via a pilot RCT with 30 HIV-infected persons assigned to the Care4Today intervention and 30 HIV-infected persons assigned to standard of care.

HIVAIDS

University of California, San Diego60 participantsStarted Oct 2013

San Diego, California, United States

TERMINATEDPhase 3< 1 mile

A Safety and Efficacy Study of Relamorelin in Diabetic Gastroparesis 01

NCT03285308

This study will evaluate the safety and efficacy of relamorelin compared to placebo in participants with diabetic gastroparesis. Participants will report daily severity scores of their diabetic gastroparesis symptoms.

GastroparesisDiabetes Mellitus

Allergan336 participantsStarted Sep 2017

Birmingham, Alabama, United States • Dothan, Alabama, United States • Huntsville, Alabama, United States +213 more locations

Care4Today v2.0 Application for Improving Adherence to HIV Medications

A Safety and Efficacy Study of Relamorelin in Diabetic Gastroparesis 01

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