Clinical Trials in San Antonio

Showing 5081-5100 of 11,125 trials

Convection-Enhanced Delivery (CED) of MDNA55 in Adults With Recurrent or Progressive Glioblastoma

NCT02858895

This is a single-arm, open-label, multicenter study in approximately 52 adults with primary (de novo) GB that has recurred or progressed (first or second recurrence, including this recurrence) after treatment(s) including surgery and radiotherapy with or without chemotherapy and following discontinuation of any previous standard or investigational lines of therapy.

GlioblastomaGrade IV AstrocytomaGlioblastoma Multiforme+1 more

Medicenna Therapeutics, Inc.47 participantsStarted Apr 2017

San Francisco, California, United States • Santa Monica, California, United States • Boca Raton, Florida, United States +4 more locations

COMPLETEDPhase 2< 1 mile

Irinotecan Hydrochloride and Temozolomide With Temsirolimus or Dinutuximab in Treating Younger Patients With Refractory or Relapsed Neuroblastoma

NCT01767194

This randomized phase II trial studies how well irinotecan hydrochloride and temozolomide with temsirolimus or dinutuximab work in treating younger patients with neuroblastoma that has returned or does not respond to treatment. Drugs used in chemotherapy, such as irinotecan hydrochloride and temozolomide, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Temsirolimus may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Monoclonal antibodies, such as dinutuximab, may find tumor cells and help kill them or carry tumor-killing substances to them. It is not yet known whether giving irinotecan hydrochloride and temozolomide together with temsirolimus or dinutuximab is more effective in treating neuroblastoma.

GanglioneuroblastomaRecurrent Neuroblastoma

National Cancer Institute (NCI)73 participantsStarted Feb 2013

Phoenix, Arizona, United States • Little Rock, Arkansas, United States • Little Rock, Arkansas, United States +154 more locations

Convection-Enhanced Delivery (CED) of MDNA55 in Adults With Recurrent or Progressive Glioblastoma

Irinotecan Hydrochloride and Temozolomide With Temsirolimus or Dinutuximab in Treating Younger Patients With Refractory or Relapsed Neuroblastoma

Find Trials by Condition in San Antonio

S1505: Combination Chemotherapy or Gemcitabine Hydrochloride and Paclitaxel Albumin-Stabilized Nanoparticle Formulation Before Surgery in Treating Patients With Pancreatic Cancer That Can Be Removed by Surgery

A Study of Experimental Medication BMS-986036 in Adults With Nonalcoholic Steatohepatitis (NASH) and Liver Cirrhosis

Precision Event Monitoring for Patients With Heart Failure Using HeartLogic

Treatments Against RA and Effect on FDG-PET/CT

Extracorporeal CO2 Removal With the Hemolung RAS for Mechanical Ventilation Avoidance During Acute Exacerbation of COPD

Safety and Efficacy Continued Access Study of the Medtronic CoreValve® System in the Treatment of Symptomatic Severe Aortic Stenosis in Very High Risk Subjects and High Risk Subjects Who Need Aortic Valve Replacement

Safety and Efficacy Study of the Medtronic CoreValve® System in the Treatment of Symptomatic Severe Aortic Stenosis in High Risk and Very High Risk Subjects Who Need Aortic Valve Replacement

Assessment of Safety, Tolerability, Immunogenicity, and Pharmacokinetics of AZD3427

Primary Tube Versus Trabeculectomy Study

Efficacy and Safety of SYNB1618 and SYNB1934 in Adult Patients With Phenylketonuria

An Investigational Study to Evaluate the Safety and Effectiveness of BMS-986165 With Background Treatment in Participants With Lupus Nephritis

A Study to Evaluate the Efficacy and Safety of Pegcetacoplan in Patients With PNH

A Study of ART24 in Subjects Recently Cured of a Clostridioides Difficile Infection (CDI)

PKUDOS: Phenylketonuria (PKU) Demographic, Outcomes, and Safety Registry

Study of Eryaspase in Combination With Chemotherapy Versus Chemotherapy Alone as 2nd-Line Treatment in PAC

Clinical Performance of Two Daily Disposable Toric Soft Contact Lenses

Stereotactic MRI-guided On-table Adaptive Radiation Therapy (SMART) for Locally Advanced Pancreatic Cancer

A Study to Assess the Efficacy and Safety of AKST4290 With Aflibercept in Patients With Newly Diagnosed nAMD