Clinical Trials in Pittsburgh

Showing 1621-1640 of 10,050 trials

Confirmatory Study of Topical HyBryte™ vs. Placebo for the Treatment of CTCL

NCT06470451

To evaluate the use of HyBryte, a topical photosensitizing agent, to treat patients with patch/plaque phase cutaneous T-cell lymphoma (mycosis fungoides).

CTCL/ Mycosis FungoidesCTCLMycosis Fungoides+1 more

Soligenix80 participantsStarted Jan 2025

Phoenix, Arizona, United States • Scottsdale, Arizona, United States • San Diego, California, United States +14 more locations

COMPLETEDPhase 2/3< 1 mile

Trametinib in Treating Patients With Recurrent or Progressive Low-Grade Ovarian Cancer or Peritoneal Cavity Cancer

NCT02101788

This phase II/III trial studies how well trametinib works and compares it to standard treatment with either letrozole, tamoxifen, paclitaxel, pegylated liposomal doxorubicin, or topotecan in treating patients with low-grade ovarian cancer or peritoneal cavity cancer that has come back (recurrent), become worse (progressive), or spread to other parts of the body. Trametinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. It is not yet known whether trametinib is more effective than standard therapy in treating patients with ovarian or peritoneal cavity cancer.

Borderline Ovarian Serous TumorMicropapillary Serous CarcinomaOvarian Serous Adenocarcinoma+3 more

National Cancer Institute (NCI)260 participantsStarted Apr 2014

Huntsville, Alabama, United States • Anchorage, Alaska, United States • Anchorage, Alaska, United States +498 more locations

Confirmatory Study of Topical HyBryte™ vs. Placebo for the Treatment of CTCL

Trametinib in Treating Patients With Recurrent or Progressive Low-Grade Ovarian Cancer or Peritoneal Cavity Cancer

Find Trials by Condition in Pittsburgh

Adolescent Attention to Emotion Study

A Study to Evaluate the Efficacy and Safety of AVTX-009 in Patients With Moderate to Severe Hidradenitis Suppurativa

A Long-term Study of Nemolizumab (CD14152) in Participants With Prurigo Nodularis (PN)

Gastroschisis Outcomes of Delivery (GOOD) Study

A Single Arm Phase II Study of ADjuvant Endocrine Therapy, Pertuzumab, and Trastuzumab for Patients With Anatomic Stage I Hormone Receptor-positive, HER2-positive Breast Cancer

A Study of Chemotherapy and Radiation Therapy Compared to Chemotherapy and Radiation Therapy Plus MEDI4736 (Durvalumab) Immunotherapy for Bladder Cancer Which Has Spread to the Lymph Nodes, INSPIRE Trial

Study of Safety and Efficacy of RGT-61159 in Adults With Relapsed/Refractory Adenoid Cystic Carcinoma (ACC) or Colorectal Carcinoma (CRC)

A Study to Assess the Long-term Efficacy and Safety of AXS-12 (Reboxetine) in Subjects With Narcolepsy (ENCORE)

Integrity Implant System Post Market Clinical Follow-Up Study

Study of COPD Subgroups and Biomarkers

STOP Persistent AF PAS

HSCT for Patients With Fanconi Anemia Using Risk-Adjusted Chemotherapy

Positive Psychology Intervention for Hematopoietic Stem Cell Transplantation Survivors

Promoting Breast Cancer Screening in Women Who Survived Childhood Cancer

Safety and Immunogenicity Trial of MPV/S-2P SARS-CoV-2 Vaccine in Adults

Return of Genomic Results and Aggregate Penetrance in Population-Based Cohorts

A Pilot Study to Assess Safety and Efficacy of SIR1-365 in Patients With Severe COVID-19

B-PaLMZ for TB Meningitis