Clinical Trials in Pittsburgh

Showing 12781-12800 of 21,047 trials

Clinical Trial of Lurbinectedin (PM01183) in Platinum Resistant Ovarian Cancer Patients

NCT02421588

Multicenter, open-label, randomized, controlled phase III clinical trial to evaluate the activity and safety of PM01183 versus PLD or topotecan as control arm in patients with platinum-resistant ovarian cancer. PM01183 will be explored as single agent in the experimental arm (Arm A) versus PLD or topotecan in the control arm (Arm B).

Ovarian Cancer

PharmaMar442 participantsStarted May 2015

Peoria, Arizona, United States • Greenbrae, California, United States • La Jolla, California, United States +25 more locations

COMPLETEDPhase 2< 1 mile

Prochymal™ Adult Human Mesenchymal Stem Cells for Treatment of Moderate-to-severe Crohn's Disease

NCT00294112

Human mesenchymal stem cells (MSCs), derived from healthy adult volunteer human donors, can be obtained from bone marrow donation and cultured in the laboratory. MSCs have shown the ability to find injured tissue, reduce and control inflammation, and assist in tissue repair. Prochymal™ MSCs will be infused into patients with moderate-to-severe Crohn's disease. Infusions will occur on two separate days, 7-10 days apart. Patients will be monitored for reduced Crohn's disease symptoms.

Crohn's Disease

Mesoblast, Inc.10 participantsStarted Mar 2006

Baton Rouge, Louisiana, United States • Charlotte, North Carolina, United States • Pittsburgh, Pennsylvania, United States +1 more locations

Clinical Trial of Lurbinectedin (PM01183) in Platinum Resistant Ovarian Cancer Patients

Prochymal™ Adult Human Mesenchymal Stem Cells for Treatment of Moderate-to-severe Crohn's Disease

Find Trials by Condition in Pittsburgh

Hydroxychloroquine for the Treatment of Hidradenitis Suppurativa

Study Comparing Test to Aczone 7.5% and Both to a Placebo Control in the Treatment of Acne Vulgaris

S0635: Erlotinib and Bevacizumab in Stage IIIB and IV Bronchioloalveolar Carcinoma

Gemcitabine With/Out Erlotinib in Unresectable Locally Advanced/Metastatic Pancreatic Cancer

Effect and Safety of Liraglutide 3.0 mg in Subjects With Overweight or Obesity and Type 2 Diabetes Mellitus Treated With Basal Insulin

Peroneal and Achilles Tendon Repair Indications With CLARIX® CORD 1K

Study of ACTR T Cell Product in Combination With Trastuzumab in Subjects With HER2-Positive Advanced Solid Tumor Cancers

Zero Degree Head Positioning in Hyperacute Large Artery Ischemic Stroke

Vaccine Therapy in Treating Patients With Breast Cancer

Examining New Diagnostic Tests for Acute Kidney Injury After Heart Surgery

Study of Oral Ixazomib in Adult Participants With Relapsed or Refractory Light Chain Amyloidosis

Efficacy of Topical Azelaic Acid 15% Gel Plus Anti-inflammatory Dose Doxycycline or Metronidazole Gel 1% Plus Anti-inflammatory Dose Doxycycline in Moderate Papulopustular Rosacea

Afatinib Treatment for Patients With EGFR Mutation Positive NSCLC Who Are Age 70 or Older

Standard Root Planing vs. Periodontal Structure Repair Device for Treatment of Pockets Caused by Periodontal Disease

An Open Single-centre Investigation Evaluating Efficacy in Second Degree Partial Thickness Burns Using a Silicone Contact Layer Containing Silver.

Group Prenatal Care for Reducing the Risk of STDs in Pregnant Young Women

Guanfacine for the Treatment of Hyperactivity in Pervasive Developmental Disorder

A Study to Evaluate Changes in Human Breast Cancer Tissue Following Short-Term Use of Darolutamide