Clinical Trials in Pittsburgh

Showing 1201-1220 of 10,050 trials

Influences of High-fiber, Organic Whole-food Formula on the Gut Microbiome in Critically Ill Children

NCT03414775

This study evaluates the effects of either Pediasure or Nourish formulas on the gastrointestinal microbiome in critically-ill children. Patients will be randomized to received either Pediasure or Nourish.

Critical IllnessDysbiosisPediatric ALL

University of Pittsburgh32 participantsStarted Feb 2018

Pittsburgh, Pennsylvania, United States

RECRUITINGNA< 1 mile

Deep Brain Stimulation Effects In Patients With Opioid Use Disorder

NCT04354077

This is a pilot study to evaluate the safety and efficacy of deep brain stimulation (DBS) of the nucleus accumbens (NAc) as adjunctive treatment for treatment-refractory opioid use disorder. This study will include 3 individuals with opioid use disorder and relapsing opioid use despite active participation in a drug addiction treatment program.

Opioid-use Disorder

Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)3 participantsStarted Feb 2022

Pittsburgh, Pennsylvania, United States

Active Not RecruitingPhase 4< 1 mile

Muscle Impact of Treating Osteoporosis

NCT05666310

Osteosarcopenia is a geriatric musculoskeletal syndrome characterized by co-existence of osteoporosis and sarcopenia (low skeletal muscle mass, strength, and/or functional capacity). There is strong evidence of overlap between the pathophysiology of osteoporosis and sarcopenia (muscle-bone crosstalk). This research plan will further explore the relationship between bone and muscle, and provide new information about effect of osteoporosis medications on muscle health in older adults who are under treatment for osteoporosis.

SarcopeniaOsteoporosis

Nami Safai Haeri20 participantsStarted Feb 2023

Pittsburgh, Pennsylvania, United States

Influences of High-fiber, Organic Whole-food Formula on the Gut Microbiome in Critically Ill Children

Deep Brain Stimulation Effects In Patients With Opioid Use Disorder

Muscle Impact of Treating Osteoporosis

Find Trials by Condition in Pittsburgh

MAAT For Young Adult Cancer Survivors

Gemcitabine Hydrochloride and Cisplatin With or Without Nab-Paclitaxel in Treating Patients With Newly Diagnosed Advanced Biliary Tract Cancers

HELIOS-B: A Study to Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

A Study to Evaluate CC-486/Onureg in Participants With Moderate or Severe Hepatic Impairment Compared With Normal Hepatic Function in Participants With Myeloid Malignancies

Study of Onvansertib in Combination With FOLFIRI and Bevacizumab or FOLFOX and Bevacizumab Versus FOLFIRI and Bevacizumab or FOLFOX and Bevacizumab for First-Line Treatment of Metastatic Colorectal Cancer in Adult Participants With a KRAS or NRAS Mutation

A Study of Brepocitinib in Adults With Active, Non-Infectious, Non-Anterior Uveitis

ASSESS ALL ALS Study

Efficacy and Safety of Selumetinib in Adults With NF1 Who Have Symptomatic, Inoperable Plexiform Neurofibromas

An Efficacy, Safety, Tolerability and Dose Finding Study of XXB750 in Resistant Hypertension Patients.

A Trial to Learn if the Combination of Fianlimab, Cemiplimab, and Chemotherapy is Safe and Works Better Than the Combination of Cemiplimab and Chemotherapy in Adult Patients With Non-Small Cell Lung Cancer That Can be Treated With Surgery

A Study of the Efficacy and Safety of Belimumab in Adults With Systemic Sclerosis Associated Interstitial Lung Disease

IC-8 Apthera IOL New Enrollment Post Approval Study

A Trial to Investigate Different Doses of Lonapegsomatropin Compared to Somatropin in Individuals With Turner Syndrome

A Phase 1 Study of UB-VV111 With and Without Rapamycin in Relapsed/Refractory CD19+ B-cell Malignancies

A Phase 1b/2, Multicenter, Open-label Study of ACP-196 in Subjects With Recurrent Glioblastoma Multiforme (GBM)

RNS System LGS Feasibility Study

Antidepressant Effects of Nitrous Oxide