Clinical Trials in Pittsburgh

Showing 1141-1160 of 10,050 trials

Virtual Reality Headset and/or Aromatherapy for Patients Undergoing a Transperineal Prostate Biopsy

NCT06296147

The purpose of this study is to evaluate if a VR headset and/or aromatherapy can be used to reduce patient pain, anxiety, and embarrassment during a transperineal biopsy (TPBx) compared to standard of care (SOC). The primary objective is to evaluate differences in self-reported pain, fear, or embarrassment during and after the procedure between the VR Group, Aromatherapy Group, VR+Aromatherapy Group, and the Control group.

Prostate Cancer

University of Pittsburgh208 participantsStarted May 2024

Pittsburgh, Pennsylvania, United States

Active Not RecruitingPhase 2< 1 mile

CROSSOVER STUDY OF ON-DEMAND PREP FORMULATIONS COMPARING RECTAL AND ORAL TENOFOVIR

NCT06560684

This is a Phase 2, multi-site, two-period, open label randomized crossover (Period 1 and 2) study. Participants are randomized 1:1 to one of two 8-week on-demand product sequences - TFV douche then oral F/TDF or oral F/TDF then TFV douche - with a 2 to 4-week washout period in between. Domains of safety, acceptability, adherence, and PK/PD (sub-study only) are assessed for each product.

Tenofovir

National Institute of Allergy and Infectious Diseases (NIAID)150 participantsStarted Oct 2024

Birmingham, Alabama, United States • Los Angeles, California, United States • Lawrenceville, Georgia, United States +5 more locations

Virtual Reality Headset and/or Aromatherapy for Patients Undergoing a Transperineal Prostate Biopsy

CROSSOVER STUDY OF ON-DEMAND PREP FORMULATIONS COMPARING RECTAL AND ORAL TENOFOVIR

Find Trials by Condition in Pittsburgh

Assessment of CCM in HF With Higher Ejection Fraction

A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

PARADIGM - En Bloc Trial With the EndoQuest Endoluminal Surgical (ELS) System

Study BT7480-100 in Patients With Advanced Malignancies Associated With Nectin-4 Expression

A Study of HC-7366 in Combination With Belzutifan (WELIREG™) in Patients With Renal Cell Carcinoma

Study to Evaluate the Safety and the Immunogenicity of a Second Generation Structurally Designed mRNA Vaccine Candidate Against Pandemic Influenza H5 HA Strain in Healthy Adult Participants Aged 18 Years and Older

Multi-Center Study of Panosyl-Isomaltooligosaccharides Adjunctive to PPI Therapy to Treat GERD

A Phase III, Safety, Tolerability and Efficacy of Combination Treatment of BL-8040 and Granulocyte Colony Stimulating Factor (G-CSF) as Compared to Placebo and G-CSF for the Mobilization of Hematopoietic Stem Cells for Autologous Transplantation in Subjects With Multiple Myeloma (MM)

Study of Orally Administered MOMA-341 in Participants With Advanced or Metastatic Solid Tumors

A Study of Cytisinicline for Smoking Cessation in Adult Smokers

Prostate Active Surveillance Study

Perf-Fix Study for Chronic Tympanic Membrane Repair

Study of the Effectiveness of Valbenazine on Patient- and Clinician-Reported Outcomes in Participants With Tardive Dyskinesia

855303-RNA Biomarker Validation

Immunotherapy With MK-3475 in Surgically Resectable Head and Neck Squamous Cell Carcinoma

The EVARREST® Pediatric Mild or Moderate Liver and Soft Tissue Bleeding Study

A Phase 1b/2, Multi-center, Single Arm Study to Assess the Safety and Efficacy of Neoantigen Synthetic Long Peptide Vaccines in Patients With Local Or Metastatic Solid Tumors

Study to Assess Safety, Tolerability and Activity of DSB2455 in Participants With Advanced Malignancies