Clinical Trials in Pittsburgh

Showing 10461-10480 of 21,047 trials

SUSTAIN-IT: Sustaining Quality of Life of the Aged: Heart Transplant or Mechanical Support?

NCT02568930

The purpose of this study is to compare health-related quality of life (HRQOL) outcomes in older (60-80 years) advanced heart failure (HF) patients who undergo heart transplantation (HT) or mechanical circulatory support (MCS) as a permanent implant (i.e., destination therapy \[DT\]) and their caregivers. Our study will contribute to better patient-centered care of older advanced HF patients and their caregivers, by informing decision making and guiding strategies to enhance post-operative HRQOL.

Heart Failure

Northwestern University694 participantsStarted Oct 2015

Birmingham, Alabama, United States • Orlando, Florida, United States • Chicago, Illinois, United States +10 more locations

COMPLETEDPhase 2< 1 mile

Copanlisib in Treating Patients With Persistent or Recurrent Endometrial Cancer

NCT02728258

This phase II trial studies how well copanlisib works in treating patients with endometrial cancer that has not decreased or disappeared, and the cancer may still be in the body despite treatment (persistent) or has come back (recurrent). Copanlisib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

Endometrial Endometrioid AdenocarcinomaEndometrial Mixed Cell AdenocarcinomaEndometrial Serous Adenocarcinoma+3 more

NRG Oncology11 participantsStarted Sep 2016

New Haven, Connecticut, United States • Deerfield Beach, Florida, United States • Miami, Florida, United States +40 more locations

SUSTAIN-IT: Sustaining Quality of Life of the Aged: Heart Transplant or Mechanical Support?

Copanlisib in Treating Patients With Persistent or Recurrent Endometrial Cancer

Find Trials by Condition in Pittsburgh

A Study of Tirzepatide (LY3298176) Versus Semaglutide Once Weekly as Add-on Therapy to Metformin in Participants With Type 2 Diabetes

Study to Explore the Safety, Tolerability and Efficacy of MK-3475 in Combination With INCB024360 in Participants With Selected Cancers

Efficacy and Safety of Adult Human Mesenchymal Stem Cells to Treat Steroid Refractory Acute Graft Versus Host Disease (GVHD)

A Study to Evaluate the Efficacy and Safety of Remdesivir Plus Tocilizumab Compared With Remdesivir Plus Placebo in Hospitalized Participants With Severe COVID-19 Pneumonia

X-82 to Treat Age-related Macular Degeneration

Multi-Dose Safety/Pharmacodynamic Study of SEL-212/SEL-037 in Subjects With Symptomatic Gout & Elevated Blood Uric Acid

Lenalidomide in Treating Older Patients With Acute Myeloid Leukemia

NA-831, Atazanavir and Dexamethasone Combination Therapy for the Treatment of COVID-19 Infection

A Dose-ranging Study to Evaluate Efficacy and Safety of VX-150 in Subjects With Acute Pain Following Bunionectomy

5-Year Safety Study of Pimecrolimus Cream 1% in Infants 3 - 12 Months of Age With Mild to Moderate Atopic Dermatitis

A Drug-Drug Interaction Study to Assess the Effect of Trametinib on the Pharmacokinetics of an Oral Contraceptive in Female Patients With Solid Tumors

A Non-Drug Study Detecting And Quantifying Nocturnal Scratch Behaviors From Wrist Actigraphy Data In Adult Healthy Volunteers And Participants With Atopic Dermatitis (AD)

Mind the Gap (AIR-B3)

Building Better Bridges Randomized Control Trial

Safety and Tolerability of WVE-120101 in Patients With Huntington's Disease

Study of Single Agent CJM112, and PDR001 in Combination With LCL161 or CJM112 in Patients With Multiple Myeloma

Novel Cardiac Signal Processing System

Study of Safety and Efficacy of AVB-S6-500 in Patients With IgA Nephropathy