Clinical Trials in Pittsburgh

Showing 981-1000 of 21,047 trials

Sleep and Circadian Interventions for College Students at High Risk of Suicide

NCT07346014

The purpose of this study is to examine the extent to which delivering sleep and circadian focused interventions in addition to evidenced based psychiatric care for depression and suicide risk may contribute to decreasing suicide risk among high risk young adults. Investigators will evaluate three interventions targeting sleep in acutely suicidal college students enrolled in intensive outpatient treatment. Participants will be randomly assigned to one of three intervention groups: 1. Triple Chronotherapy (TCT)+ Transdiagnostic Sleep and Circadian Intervention (TSC) 2. Transdiagnostic Sleep and Circadian Intervention (TSC) 3. Sleep Feedback (SF) Participants will be followed for 6 months with primary outcome domains of suicidal thoughts and behaviors and depression evaluated by blinded clinicians at short (Days 1-4 of intervention), medium (2 months) and long (6 month) term intervals.

Sleep DisturbanceSleepDepression+1 more

University of Pittsburgh90 participantsStarted Jun 2026

Pittsburgh, Pennsylvania, United States

COMPLETEDPhase 1< 1 mile

A Study of MK-8527 in Healthy Lactating Female Participants (MK-8527-009)

NCT06580587

The goal of this study is to learn how MK-8527 moves through the healthy person's body over time. Researchers will measure for the amount of MK-8527 in breast milk that the baby will receive at many time points.

HealthyHIV Pre-exposure Prophylaxis

Merck Sharp & Dohme LLC13 participantsStarted Apr 2025

Springfield, Missouri, United States • Pittsburgh, Pennsylvania, United States

Sleep and Circadian Interventions for College Students at High Risk of Suicide

A Study of MK-8527 in Healthy Lactating Female Participants (MK-8527-009)

Find Trials by Condition in Pittsburgh

Development of a Database to Investigate Digital and Blood-Based Biomarkers and Their Relationship to Tau and Amyloid PET Imaging in Older Participants Who Are Cognitively Normal (CN), Have Mild Cognitive Impairment (MCI), or Have Mild-to-Moderate AD Dementia

A Study of Aticaprant in Adult and Elderly Participants With Major Depressive Disorder (MDD)

MeSenteric SpAring Versus High Ligation Ileocolic Resection for the Prevention of REcurrent Crohn's DiseaSe (SPARES)

A Study With a Initial Treatment Period Followed by a Randomized-withdrawal Period to Evaluate the Efficacy and Safety of Bimekizumab in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis

Low-Dose Radiotherapy For Patients With SARS-COV-2 (COVID-19) Pneumonia

The Willow LTE Study With M5049 in Participants With SCLE, DLE and/or SLE (WILLOW LTE)

A Study to Investigate the Safety and Effectiveness of a Coagulation Factor IX Gene Insertion Therapy (REGV131-LNP1265) in Pediatric, Adolescent and Adult Participants With Hemophilia B

Acalabrutinib Monotherapy vs Investigator's Choice of Treatment in Patients With CL Leukaemia and Heart Failure

Study of Zelenectide Pevedotin in Participants With Advanced Breast Cancer

MED-EL Remote Care Multi-Center Feasibility Study

A Study to Evaluate the Efficacy and Safety of Bimekizumab in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis

A Study to Learn How Safe and Effective Risankizumab is When Compared to Deucravacitinib to Treat Participants With Moderate Plaque Psoriasis and Who Need to Try Systemic Treatment (Works Throughout the Whole Body)

Study of GS-9911 With or Without Antibody Treatment for Adults With Solid Tumors

Ribociclib (LEE011) Rollover Study for Continued Access

Prediction Augmented Screening Initiative

A Phase 1, Dose Escalation Trial of RP-A601 in Subjects With PKP2 Variant-Mediated Arrhythmogenic Cardiomyopathy (PKP2-ACM)

Phase II Study of Second- Line Pembrolizumab Plus GVD for Relapsed or Refractory Hodgkin Lymphoma

A Safety Surveillance Study in Subjects With Macular Degenerative Disease Treated With Human Embryonic Stem Cell-derived Retinal Pigment Epithelial Cell Therapy