Clinical Trials in Pittsburgh

Showing 7961-7980 of 21,047 trials

Oral AHR Antagonist in Combination With Nivolumab in Patients With PD-1 Resistant Metastatic or Recurrent Head and Neck Cancer

NCT05472506

This is a phase 1b study in adult patients diagnosed with resistant or recurrent head and neck squamous cell carcinoma (HNSCC) designed to assess the safety and tolerability of IK-175 in combination with nivolumab. Disease response, pharmacokinetics (PK), pharmacodynamics, and response biomarkers will also be assessed.

Head and Neck Squamous Cell CarcinomaHead and Neck CancerHead Cancer+3 more

Ikena OncologyStarted Mar 2023

Chicago, Illinois, United States • St Louis, Missouri, United States • Pittsburgh, Pennsylvania, United States +1 more locations

COMPLETEDNA< 1 mile

A Mindfulness Approach to UA for Afro-descendants

NCT05881681

The goal of this clinical trial is to test an app-based mindfulness training program in an Afro-descendant population. The main question\[s\] it aims to answer are: * What changes, if any, does the app need? * Is it effective in reducing anxiety among this population? Participants will be asked to: * Use an app-based mindfulness training program daily * Complete online surveys at baseline and 2 months post-treatment initiation * Complete focused interviews via Zoom at baseline and 2 months post-treatment initiation * Complete daily voice diaries via Zoom

AnxietyStress

Brown University15 participantsStarted Sep 2022

Pittsburgh, Pennsylvania, United States

Oral AHR Antagonist in Combination With Nivolumab in Patients With PD-1 Resistant Metastatic or Recurrent Head and Neck Cancer

A Mindfulness Approach to UA for Afro-descendants

Find Trials by Condition in Pittsburgh

A Study to Evaluate the Effect of Testosterone Replacement Therapy (TRT) on the Incidence of Major Adverse Cardiovascular Events (MACE) and Efficacy Measures in Hypogonadal Men

Avelumab in Participants With Merkel Cell Carcinoma (JAVELIN Merkel 200)

Robotic-assisted and Laparoscopic Right Colectomy Study - Intracorporeal vs. Extracorporeal Anastomoses

Oral Infigratinib for the Adjuvant Treatment of Subjects With Invasive Urothelial Carcinoma With Susceptible FGFR3 Genetic Alterations

Osimertinib With Stereotactic Radiosurgery (SRS) in Brain Metastases From EGFR Positive NSCLC

Evaluation of the PrevisEA Device for Predicting Gastrointestinal Impairment

Long-term Access Program (LAP) of Mepolizumab for Subjects Who Participated in Study MEA115921

Study to Evaluate Amifampridine Phosphate in Patients With MuSK-MG

A Safety and Tolerability Study of NC318 in Subjects With Advanced or Metastatic Solid Tumors

A Study of Ocrelizumab in Comparison With Interferon Beta-1a (Rebif) in Participants With Relapsing Multiple Sclerosis

Study to Assess the Efficacy and Safety of Emapalumab in Primary Haemophagocytic Lymphohistiocytosis

Platform Sub-study of Belantamab Mafodotin (GSK2857916) in Combination With aOX40 (GSK3174998) in Participants With RRMM

Multi-center Phase I/IIa Trial of an Autologous Tumor Lysate (TL) + Yeast Cell Wall Particles (YCWP) + Dendritic Cells (DC) Vaccine in Addition to Standard of Care Checkpoint Inhibitor of Choice in Metastatic Melanoma Patients With Measurable Disease.

Prospective SPINE Registry

Association of Platelet Parameters With Bleeding Severity in Children With ITP

A Study of Purified Inactivated Zika Virus Vaccine (PIZV) in Healthy Adults

A Study of hSTC810 With Advanced/Metastatic Solid Tumors (STCUBE-001)

Losmapimod Safety and Efficacy in COVID-19