Clinical Trials in Pittsburgh

Showing 7781-7800 of 16,007 trials

Transfusion of Biotin-Labeled Red Blood Cells

NCT03364686

The purpose of this research is to evaluate the impact of genetic and biologic factors in blood donors on red blood cell storage stability after autologous transfusion over the different range of storage period of 5-7 days and 35-42 days in healthy volunteers.

Healthy Volunteers

Gladwin, Mark, MD6 participantsStarted Sep 2019

Pittsburgh, Pennsylvania, United States

COMPLETEDPhase 2< 1 mile

Study of Durvalumab (MEDI4736) After Chemo-Radiation for Microsatellite Stable Stage II-IV Rectal Cancer

NCT03102047

This study is being done to look at the safety and response to the investigational drug durvalumab (MEDI4736) following chemo-radiation therapy for patients with MSS stage II to IV rectal cancer. Durvalumab recognizes specific proteins on the surface of cancer cells and triggers the immune system to destroy the cancer cells. The chemoRT portion of the treatment will be completed just before the course of durvalumab is initiated. In order to learn more about certain characteristics of rectal cancer tumors, this study includes special research tests using samples from diagnostic tumors, a tissue sample from tumors removed during surgery, fresh tumor samples from an area where the cancer has recurred, and blood samples.

Rectal Cancer

NSABP Foundation Inc45 participantsStarted May 2018

Guilford, Connecticut, United States • New Haven, Connecticut, United States • New Haven, Connecticut, United States +40 more locations

Transfusion of Biotin-Labeled Red Blood Cells

Study of Durvalumab (MEDI4736) After Chemo-Radiation for Microsatellite Stable Stage II-IV Rectal Cancer

Find Trials by Condition in Pittsburgh

A Safety, Tolerability, and Pharmacokinetics Study of a Single Intravenous Injection of Recombinant Coagulation Factor VIII Fc - Von Willebrand Factor - XTEN Fusion Protein (rFVIIIFc-VWF-XTEN) (BIVV001) in Previously Treated Adults With Severe Hemophilia A (EXTEN-A)

A Study to Compare BMS-936558 to the Physician's Choice of Either Dacarbazine or Carboplatin and Paclitaxel in Advanced Melanoma Patients That Have Progressed Following Anti-CTLA-4 Therapy (CheckMate 037)

The Product Surveillance Registry REVERSE Post Approval Study

Docetaxel and Cyclophosphamide Compared to Anthracycline-Based Chemotherapy in Treating Women With HER2-Negative Breast Cancer

Low-Level Laser Therapy for Prevention of Oral Mucositis

Olaparib Tablets as a Treatment for Ovarian Cancer Subjects With Different HRD Tumor Status

Efficacy and Safety of Finerenone in Subjects With Type 2 Diabetes Mellitus and the Clinical Diagnosis of Diabetic Kidney Disease

Biological and Clinical Effects of Palbociclib With Ovarian Suppression and Letrozole in the Neoadjuvant Treatment of Breast Cancer

PMCF Study on PEEK Suture Anchors for Shoulder Indications

Mino-Lok Therapy (MLT) for the Treatment of CRBSI/CLABSI

Supported Employment Demonstration

A Study of Budigalimab (ABBV-181) in Participants With Advanced Solid Tumors

Study of Denileukin Diftitox in Participants With Stage IIIC and Stage IV Melanoma

An Observational Study of Long-term Outcomes of HIV-1 Infection in Persons Who Become HIV-1 Infected After Enrollment in HIV-1 Vaccine Trials

A Study to Assess Efficacy and Safety of HL036 in Subjects With Dry Eyes

Rollover Study for Continuing NBI-98854 Administration in Pediatric Subjects With Tourette Syndrome

SMS Maama Project COVID-19

Revealed Versus Concealed Cerebroplacental Ratio