Clinical Trials in Pittsburgh

Showing 7181-7200 of 21,047 trials

Epigenetic Effects on Traumatic Brain Injury Recovery

NCT04186429

Methylation of the brain-derived neurotrophic factor (BDNF) gene is involved in both the biological encoding of childhood adversity and neuroplasticity following traumatic brain injury (TBI). This research will characterize BDNF methylation during recovery from TBI in children and investigate this novel biomarker as a potential biological mechanism underlying the known association between childhood adversity and poorer neurobehavioral outcomes following TBI in childhood. Findings from this research will contribute to an improved understanding of why some children display good recovery following TBI, whereas many others suffer from chronic neurobehavioral impairments.

Traumatic Brain InjuryOrthopedic Injury

University of Pittsburgh401 participantsStarted Jul 2017

Pittsburgh, Pennsylvania, United States

COMPLETEDNA< 1 mile

Staying Active With Arthritis: RCT of Physical Activity for Older Adults With Osteoarthritis and Hypertension

NCT01280903

The purpose of the Staying Active with Arthritis (STAR) research study is to determine if a 6-month program will improve leg exercise, fitness walking, and clinical outcomes (function, blood pressure, leg strength, pain, fatigue, and health-related quality of life) in older adults with osteoarthritis of the knee and high blood pressure.

Osteoarthritis, KneeHypertension

University of Pittsburgh182 participantsStarted Jan 2012

Pittsburgh, Pennsylvania, United States

Epigenetic Effects on Traumatic Brain Injury Recovery

Staying Active With Arthritis: RCT of Physical Activity for Older Adults With Osteoarthritis and Hypertension

Find Trials by Condition in Pittsburgh

A Study of CC-95251, a Monoclonal Antibody Directed Against SIRPα, in Participants With Advanced Solid and Hematologic Cancers

IMP4297 in Combination With Temozolomide in Patients With Advanced Solid Tumors and Small Cell Lung Cancer

Dalbavancin for the Treatment of Acute Bacterial Skin and Skin Structure Infections in Children, Known or Suspected to be Caused by Susceptible Gram-positive Organisms, Including MRSA

A Study of Atezolizumab as Neoadjuvant and Adjuvant Therapy in Resectable Non-Small Cell Lung Cancer (NSCLC) - Lung Cancer Mutation Consortium (LCMC3)

Zephyrus I: Evaluation of Efficacy and Safety of Pamrevlumab in Participants With Idiopathic Pulmonary Fibrosis (IPF)

A Study to Evaluate Treatment Satisfaction With Erenumab in Participants With Migraine

Phase IIa Study Evaluating Safety and Efficacy of BL-8040 in Relapsed/Refractory AML Patients

Long-term Safety of Lumacaftor/Ivacaftor in Participants With Cystic Fibrosis Who Are Homozygous for F508del and 12 to <24 Months of Age at Treatment Initiation

A Study to Evaluate Analgesic Efficacy and Safety of PRF-110 for Post-surgical Pain

Feasibility of Home Instillation of UGN-102 for Treatment of Low-Grade (LG) Non-Muscle Invasive Bladder Cancer (NMIBC)

First-in-Human Study of EOS100850 (Inupadenant) in Patients with Cancer

Study to Evaluate Treatment Compliance, Efficacy and Safety of an Improved Deferasirox Formulation (Granules) in Pediatric Patients (2-<18 Years Old) With Iron Overload

Natural History Study of ENPP1 Deficiency and the Early-onset Form of ABCC6 Deficiency

Pilot Trial of the RUBI Program for Autistic Adults

Peer Mentorship to Improve Outcomes in Patients on Maintenance Hemodialysis

TelemEdiciNe-bAsed Cognitive TherapY for Migraines

Clinical Trial Comparing C-Brace to Knee Ankle Foot Orthosis (KAFO)/Stance Control Orthosis (SCO)

A Study to Evaluate the Efficacy, Safety, and Concentration of SNS812 in Mild to Moderate COVID-19 Patients