Clinical Trials in Pittsburgh

Showing 7121-7140 of 16,007 trials

Cytochrome C Oxidase Activity in Newly Diagnosed Glioblastoma Multiforme (GBM)

NCT02997423

This is a multi-institutional, consortium-based, non-interventional prospective blinded endpoints clinical study to determine whether high activity of Cytochrome C Oxidase (CcO) in tumor specimens from subjects with newly diagnosed primary GBM is associated with shortened OS (primary outcome) and PFS (secondary outcome) times.

Glioblastoma

University of Iowa153 participantsStarted Nov 2016

Birmingham, Alabama, United States • Sacramento, California, United States • Miami, Florida, United States +16 more locations

COMPLETEDPhase 3< 1 mile

Clostridium Difficile Vaccine Efficacy Trial

NCT03090191

The Clover trial is evaluating an investigational vaccine that may help to prevent Clostridium difficile infection. Participants in the study are adults 50 years of age and older, who are at risk of developing Clostridium difficile infection. The study will assess whether the vaccine prevents the disease, and whether it is safe and well tolerated. Each subject will receive 3 doses of Clostridium difficile vaccine or placebo and be followed for up to 3 years after vaccination for potential Clostridium difficile infection.

Clostridium Difficile Infection

Pfizer17,535 participantsStarted Mar 2017

Athens, Alabama, United States • Huntsville, Alabama, United States • Mobile, Alabama, United States +423 more locations

Cytochrome C Oxidase Activity in Newly Diagnosed Glioblastoma Multiforme (GBM)

Clostridium Difficile Vaccine Efficacy Trial

Find Trials by Condition in Pittsburgh

Safety and Efficacy Study of Sapanisertib in Combination With Exemestane or Fulvestrant in Postmenopausal Women With Estrogen Receptor Positive/Human Epidermal Growth Factor Receptor 2 Negative (ER+/HER2-) Metastatic Breast Cancer

Study of BMS-936558 (Nivolumab) Compared to Docetaxel in Previously Treated Metastatic Non-squamous NSCLC

Phase 3 Study of Adjunctive Ganaxolone in Adults With Drug-resistant Partial Onset Seizures and Open-label Extension

Efficacy & Safety of Abaloparatide-Solid Microstructured Transdermal System in Postmenopausal Women With Osteoporosis

Efficacy, Safety and Tolerability of AVP-786 for the Treatment of Agitation in Patients With Dementia of the Alzheimer's Type

Access Natriuretic Peptide Assay(s) Pivotal - Emergency Department Subject Enrollment and Specimen Collection

Safety, Tolerability, and Pharmacokinetics of Oral NX-13 in Active Ulcerative Colitis

A Research Study to Compare Two Doses of Semaglutide Taken Once Weekly in People With Type 2 Diabetes

Study of Evinacumab (REGN1500) in Participants With Persistent Hypercholesterolemia

Improving Quality by Maintaining Accurate Problems in the EHR

A Study of Gantenerumab in Participants With Mild Alzheimer Disease

A Study to Evaluate OP-101 (Dendrimer N-acetyl-cysteine) in Severe Coronavirus Disease 2019 (COVID-19) Patients

Safety, Tolerability, and Efficacy of TAK-659 in Adults With Relapsed or Refractory Acute Myelogenous Leukemia (AML)

A First-in-Human Study of CDK-002 (exoSTING) in Subjects With Advanced/Metastatic, Recurrent, Injectable Solid Tumors

Evaluating an Emergency Department Observation Syncope Protocol for Older Adults

Web-based Implementation for the Science of Enhancing Resilience Study

Botulinum Toxin Versus Placebo Injections to Temporalis and Masseter Muscles

Coenzyme Q10 Phase III Trial in Gulf War Illness