Clinical Trials in Pittsburgh

Showing 6601-6620 of 16,007 trials

Trial of Fistula Versus Graft in Elderly Patients

NCT03668002

This open-label pilot randomized controlled trial will test the feasibility and safety of randomizing patients over 65 years old who start hemodialysis with a tunneled dialysis catheter (TDC), and are eligible to receive either arteriovenous fistula (AVF) or arteriovenous graft (AVG), to an AVF strategy (comparator) or to an AVG strategy (intervention). The primary outcome is feasibility, which we will assess by measuring: (1) the proportion of randomized participants who receive the assigned arteriovenous access; and (2) the annual rate of enrollment in the study, accounting for the number of surgeons who participate. Secondary outcomes will include perioperative morbidity and mortality, catheter removal rates, additional procedures performed, and the reasons a patient may not receive the assigned AV access.

End Stage Renal DiseaseArteriovenous FistulaArteriovenous Graft

University of Pittsburgh21 participantsStarted Sep 2018

Pittsburgh, Pennsylvania, United States

TERMINATEDPhase 1/2< 1 mile

Safety and Clinical Activity of Nivatrotamab in Relapsed/Recurrent Metastatic Small-cell Lung Cancer

NCT04750239

Adult patients with small-cell lung cancer (SCLC) will be treated with nivatrotamab a monoclonal anti GD2×CD3 bispecific antibody to investigate the safety and tolerability of the drug.

SCLC

Y-mAbs Therapeutics3 participantsStarted Aug 2021

Tampa, Florida, United States • Atlanta, Georgia, United States • Detroit, Michigan, United States +4 more locations

Trial of Fistula Versus Graft in Elderly Patients

Safety and Clinical Activity of Nivatrotamab in Relapsed/Recurrent Metastatic Small-cell Lung Cancer

Find Trials by Condition in Pittsburgh

KUR-113 Bone Graft Versus Local Autograft for the Treatment of Single-level Transforaminal Lumbar Interbody Fusion

Coolief Cooled Radiofrequency vs. Conventional Radiofrequency to Manage OA Knee Pain

Safety, Tolerability, and Efficacy of Aflibercept in Patients With Neovascular Age-Related Macular Degeneration

Retrospective Independent Safety Review of Closed Irrisept Study

A Study of Tucatinib vs. Placebo in Combination With Capecitabine & Trastuzumab in Patients With Advanced HER2+ Breast Cancer

A Safety, Efficacy and Systemic Exposure Study of CD5789 Cream in Adults and Adolescents With Lamellar Ichthyosis

Safety and Immunogenicity of AdCOVID in Healthy Adults (COVID-19 Vaccine Study)

Study of Cingal® and Triamcinolone Hexacetonide for the Relief of Knee Osteoarthritis Pain

Software Treatment for Actively Reducing Severity of ADHD in Adolescents (STARS-ADHD-Adolescents)

Evaluation of NanoDoce® in Participants With Urothelial Carcinoma

A Study of FT-7051 in Men With MCRPC

A Randomized, Double-blind, Placebo Controlled Phase III Study to Investigate Efficacy and Safety of First-Line Treatment With HLX10 + Chemotherapy (Carboplatin-Nanoparticle Albumin Bound (Nab) Paclitaxel) in Patients With Stage IIIB/IIIC or IV NSCLC

RObotic Versus LAparoscopic Resection for Rectal Cancer

A Study of Adavosertib as Treatment for Uterine Serous Carcinoma

ADVM-022 Intravitreal Gene Therapy for Wet AMD

Dose Optimization Study of Idelalisib in Follicular Lymphoma

Evaluation of Protease Inhibition for COVID-19 in Standard-Risk Patients (EPIC-SR).

A Clinical Study of Cobimetinib Administered in Combination With Niraparib, With or Without Atezolizumab to Patients With Advanced Platinum-sensitive Ovarian Cancer