Clinical Trials in Pittsburgh

Showing 5321-5340 of 16,007 trials

Rural Access to Physical Therapy for Osteoarthritis Rehabilitation - Pilot

NCT05114512

This is a pilot study involving a hybrid in-person + telerehabilitation intervention for rural adults with knee osteoarthritis. The primary purpose is to demonstrate feasibility and safety of the RAPTOR program, and the secondary purpose is to estimate clinical effectiveness of the RAPTOR program on participants' pain, function, and quality of life.

Osteoarthritis, Knee

University of Pittsburgh27 participantsStarted Dec 2021

Pittsburgh, Pennsylvania, United States

COMPLETEDNA< 1 mile

Development and Feasibility Testing of a Suicide Prevention Intervention for Sexual and Gender Minority Youth

NCT05724784

This study aims to develop and test a brief, digital, suicide prevention intervention for sexual and gender minority (SGM) youth who have experienced cyberbullying. Leading up to this phase, the study team completed two prior study aims, focused on identifying perspectives of SGM youth's regarding their experiences with cyberbullying and priorities for an intervention, and a phase in which SGM youth codesigned the study's intervention with the study team. This resulted in the development of study's intervention, Flourish, which leverages a text messaging-based chatbot to reduce suicide risk following cyberbullying among SGM youth through improving distress tolerance, motivation for help-seeking, and social problem-solving. Current Study Aim: Conduct an open trial to assess the feasibility and acceptability of Flourish among cyberbullied SGM youth, ages 12-17 (N=10). Hypotheses: Feasibility will be evidenced by recruitment/retention rates \> 80% and use of Flourish among \> 70% of SGM youth. At follow-up, adolescents will report improved problem-solving capacity, distress tolerance, and motivation for help-seeking and reduced psychological distress and suicidal ideation compared to baseline.

Psychological DistressSuicidal Ideation

University of Pittsburgh11 participantsStarted May 2023

Pittsburgh, Pennsylvania, United States

Rural Access to Physical Therapy for Osteoarthritis Rehabilitation - Pilot

Development and Feasibility Testing of a Suicide Prevention Intervention for Sexual and Gender Minority Youth

Find Trials by Condition in Pittsburgh

Optimizing Outcomes of Treatment-Resistant Depression in Older Adults

Thinking in Speech for Children With Autism

A Phase 3 Study of VX-121 Combination Therapy in Participants With Cystic Fibrosis (CF) Heterozygous for F508del and a Minimal Function Mutation (F/MF)

Study to Evaluate the Safety and Efficacy of Lenacapavir (GS-6207) in Combination With Other Antiretroviral Agents in People Living With HIV

Acute Effects of Paraxanthine on Energy and Focus

A Clinical Study of an Investigational Drug for the Treatment of Major Depressive Episode Associated With Bipolar I Disorder.

Observational Study of Obstructive Lung Disease (NOVELTY)

Wearable Assessments in the Clinic and Home in PD

REmodeling the Left Ventricle With Atrial Modulated Pacing

Safety and Anti-Tumor Activity of TYRA-200 in Advanced Cholangiocarcinoma With Activating FGFR2 Gene Alterations

Trial of PDE4 Inhibition With Roflumilast for the Management of Atopic Dermatitis

Open- Label Trial of Sipuleucel-T Administered to Active Surveillance Patients for Newly Diagnosed Prostate Cancer

A Study Evaluating the Effect of Filgotinib Dose De-escalation in Participants With Ulcerative Colitis (UC) in Remission

A Study of LY3002813 in Participants With Memory Damage Due to Alzheimer's Disease (AD) or AD

A Randomized Trial of Recruitment Strategies for Research Participation

Phase I/II Eval Safety & Prelim Activity Nivolumab Comb W/Vorolanib Pts W/Refractory Thoracic Tumors

A Phase 1, Dose Escalation Trial of RP-A601 in Subjects With PKP2 Variant-Mediated Arrhythmogenic Cardiomyopathy (PKP2-ACM)

The Neonatal Hemorrhagic Risk Assessment in Thrombocytopenia