Clinical Trials in Pittsburgh

Showing 5141-5160 of 16,007 trials

Hemodynamic Evaluation of Levosimendan in Patients With PH-HFpEF

NCT03541603

Phase 2 study to evaluate the efficacy and safety of intermittent levosimendan compared with placebo in hemodynamic improvement with exercise in PH-HFpEF subjects

Hypertension Pulmonary SecondaryHeart Failure, Right SidedHeart Failure With Normal Ejection Fraction

Tenax Therapeutics, Inc.44 participantsStarted Nov 2018

Stanford, California, United States • Chicago, Illinois, United States • Boston, Massachusetts, United States +13 more locations

Active Not RecruitingPhase 3< 1 mile

A Study to Compare the Efficacy and Safety of Luspatercept (ACE-536) Versus Epoetin Alfa for the Treatment of Anemia Due to IPSS-R Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Participants Who Require Red Blood Cell Transfusions and Are ESA Naïve

NCT03682536

The purpose of this study is to determine the effectiveness of luspatercept (ACE-536) compared to epoetin alfa on red blood cell (RBC) transfusion independence (for at least 12 weeks) with a concurrent hemoglobin increase of at least 1.5 g/dL in participants with anemia due to revised international prognostic scoring system (IPSS-R) very low, low, or intermediate risk myelodysplastic syndromes (MDS) who require RBC transfusions and have never been exposed to erythropoiesis stimulating agent (ESA).

Myelodysplastic Syndromes

Celgene363 participantsStarted Jan 2019

Berkeley, California, United States • San Diego, California, United States • Whittier, California, United States +223 more locations

Hemodynamic Evaluation of Levosimendan in Patients With PH-HFpEF

A Study to Compare the Efficacy and Safety of Luspatercept (ACE-536) Versus Epoetin Alfa for the Treatment of Anemia Due to IPSS-R Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Participants Who Require Red Blood Cell Transfusions and Are ESA Naïve

Find Trials by Condition in Pittsburgh

Efficacy and Safety of Pegzilarginase in Patients With Arginase 1 Deficiency

Gemcitabine Hydrochloride With or Without Vismodegib in Treating Patients With Recurrent or Metastatic Pancreatic Cancer

A Study of AGS-16C3F vs. Axitinib in Metastatic Renal Cell Carcinoma

A Study of Oral Ixazomib Citrate (MLN9708) Maintenance Therapy in Participants With Multiple Myeloma Following Autologous Stem Cell Transplant

Zip-Stitch® in Minimally-Invasive Surgery (ZIMS) - Safety & Efficacy in Hysterectomy

Assessment of the Efficacy, Safety, and Tolerability of AVP-786 (Deudextromethorphan Hydrobromide [d6-DM]/Quinidine Sulfate [Q]) for the Treatment of Agitation in Patients With Dementia of the Alzheimer's Type

The Study of Nasal Insulin in the Fight Against Forgetfulness (SNIFF)

A Study of Intravenous and Oral Isavuconazonium Sulfate in Pediatric Patients

Rollover Study for Subjects Who Have Participated in an Astellas Sponsored ASP2215 Trial

A Study Evaluating the Safety and Efficacy of Brexucabtagene Autoleucel (KTE-X19) in Adult Subjects With Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia (ZUMA-3)

Study of the Oral Factor D (FD) Inhibitor ALXN2050 in PNH Patients as Monotherapy

Galinpepimut-S in Combination With Pembrolizumab in Patients With Selected Advanced Cancers

A Long-Term Safety Follow-Up Study for Patients Treat With WU-CART-007

Pediatric Cardiac Output Monitoring Observational Study

Age of Blood in Sickle Cell Transfusion

A Study to Learn About the Study Medicine (Called PF-07220060 in Combination With PF-07104091) In Participants With Breast Cancer and Solid Tumors

A Randomized, Placebo-controlled, Double-blind Phase 2 Study With OSI-906 in Patients With Advanced HCC

RO4929097 and Whole-Brain Radiation Therapy or Stereotactic Radiosurgery in Treating Patients With Brain Metastases From Breast Cancer