Clinical Trials in Pittsburgh

Showing 4861-4880 of 21,047 trials

An Efficacy, Safety, and Tolerability Study of VX-880 in Participants With Type 1 Diabetes With a Kidney Transplant

NCT06832410

This study will evaluate the efficacy, safety, and tolerability of VX-880 in participants with Type 1 Diabetes (TID) with a kidney transplant.

Type 1 DiabetesKidney Transplant

Vertex Pharmaceuticals Incorporated10 participantsStarted Mar 2025

Philadelphia, Pennsylvania, United States • Pittsburgh, Pennsylvania, United States • Madison, Wisconsin, United States +4 more locations

COMPLETED115 miles

Sickle Cell Disease, Hemechip

NCT03948516

Sickle cell disease is very common in Nigeria. Early diagnosis is important to prevent or reduce serious complications from the disease and to enable children stay healthy. To this end, the investigators would like to test a new, simple and quick device called the HemeChip to determine if it can detect whether or not someone has sickle cell disease. The investigators will compare the results obtained with the HemeChip with a standard method of diagnosing sickle cell disease known as Isoelectric focusing (IEF) or High Performance Liquid Chromatography (HPLC).If the investigators show that the new device can differentiate between children who have sickle cell disease and those who don't as successfully as the IEF or HPLC, they estimate a sharp increase in the use of this device in many countries especially in Africa due to its lower cost

Sickle Cell Disease

University Hospitals Cleveland Medical Center738 participantsStarted Jul 2017

Omaha, Nebraska, United States • Chapel Hill, North Carolina, United States • Cleveland, Ohio, United States +4 more locations

An Efficacy, Safety, and Tolerability Study of VX-880 in Participants With Type 1 Diabetes With a Kidney Transplant

Sickle Cell Disease, Hemechip

Find Trials by Condition in Pittsburgh

Defining the Genetic Etiology of Suppurative Lung Disease in Children and Adults

Evaluating the Infectivity, Safety and Immunogenicity of a Recombinant Live-Attenuated Respiratory Syncytial Virus Vaccine, LID/ΔM2-2/1030s, in RSV-Seronegative Infants and Children 6 to 24 Months of Age

Trial of Mosunetuzumab (BTCT4465A) as Consolidation Therapy in Participants With Diffuse Large B-Cell Lymphoma Following First-Line Immunochemotherapy and as Monotherapy or in Combination With Polatuzumab Vedotin in Elderly/Unfit Participants With Previously Untreated Diffuse Large B-Cell Lymphoma

A Study of LY3039478 in Participants With Advanced or Metastatic Solid Tumors

A Proof-of-concept Study of the Efficacy and Safety of Nipocalimab in Participants With Active Rheumatoid Arthritis

Characterizing the Upper Airway Manifestations in Primary Ciliary Dyskinesia and Primary Immunodeficiencies

STICH3C Cardiac Magnetic Resonance Observational Study

Vein of Marshall Ethanol Infusion for Persistent Atrial Fibrillation

Hospital Implementation of a Stroke Protocol for Emergency Evaluation and Disposition

[177Lu]Lu-NeoB in Combination With Ribociclib and Fulvestrant in Participants With ER+, HER2- and GRPR+ Advanced Breast Cancer

A Study Assessing KB407 for the Treatment of Cystic Fibrosis

A Study to Evaluate the Effect of Ustekinumab on Cytochrome P450 Enzyme Activities Following Induction and Maintenance Dosing in Participants With Active Crohn's Disease or Ulcerative Colitis

INCB050465 in Combination With Rituximab, Bendamustine and Rituximab, or Ibrutinib in Participants With Previously Treated B-Cell Lymphoma (CITADEL-112)

Oral Contraceptive Pill (OCP) Pharmacogenomics

Families Left Behind

Clinical Study Evaluating Nordlys™ SWT IPL for Dry Eye Disease (DED) Due to MGD

Clinical Study to Evaluate the Safety and Efficacy of Candela Technology

The ReTAVI Prospective Observational Registry