Clinical Trials in Pittsburgh

Showing 441-460 of 10,050 trials

MR-Adaptive Radiation Therapy for Anal Cancer With EScalated-Treatment in a Risk-Optimized Approach

NCT06050707

The proposed study is a phase II, single arm, open-label trial of MR-guided radiation therapy (RT) with risk stratified RT dose selection in patients with anal cancer. Based on previous data, a risk adaptive treatment approached is proposed in 4 groups: Low risk, standard risk, intermediate risk, and high risk. Human papillomavirus (HPV) DNA will be analyzed to identify novel biomarkers that predict chemoradiotherapy (CRT) response and toxicity.

Anal Squamous Cell Carcinoma

University Health Network, Toronto80 participantsStarted Sep 2023

Pittsburgh, Pennsylvania, United States • Milwaukee, Wisconsin, United States • Heidelberg, Victoria, Australia +1 more locations

RECRUITINGPHASE2< 1 mile

A Study Evaluating Persistence of the Immune Response of the Adjuvanted Respiratory Syncytial Virus (RSV) Vaccine and the Safety and Immune Response Following Revaccination in Adults 18 Years of Age and Above Who Received Lung or Kidney Transplant

NCT07092865

This study evaluates persistence of the immune response of the adjuvanted RSV vaccine and the safety and immunogenicity following revaccination in adults 18 years of age and above who received lung or kidney transplant.

Respiratory Syncytial Virus Infections

GlaxoSmithKline184 participantsStarted Aug 2025

Lexington, Kentucky, United States • St Louis, Missouri, United States • St Louis, Missouri, United States +34 more locations

MR-Adaptive Radiation Therapy for Anal Cancer With EScalated-Treatment in a Risk-Optimized Approach

A Study Evaluating Persistence of the Immune Response of the Adjuvanted Respiratory Syncytial Virus (RSV) Vaccine and the Safety and Immune Response Following Revaccination in Adults 18 Years of Age and Above Who Received Lung or Kidney Transplant

Find Trials by Condition in Pittsburgh

Higher Per Daily Treatment-Dose Radiation Therapy or Standard Per Daily Treatment Radiation Therapy in Treating Patients With Early-Stage Breast Cancer That Was Removed by Surgery

FOLFIRI or Modified FOLFIRI and Veliparib as Second Line Therapy in Treating Patients With Metastatic Pancreatic Cancer

Medtronic Terminate AF Study

A Study to Assess the Long-term Safety and Efficacy of ATB200/AT2221 in Adult Subjects With Late-Onset Pompe Disease (LOPD)

A Surveillance Study of Susceptibility to Baloxavir Marboxil in Pediatric Participants With Influenza and Transmission of Influenza to Household Contacts

Interstitial Brachytherapy With or Without External-Beam Radiation Therapy in Treating Patients With Prostate Cancer

Cediranib Maleate and Olaparib in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Peritoneal Cancer or Recurrent Triple-Negative Breast Cancer

Study of AZD0516 as Monotherapy and in Combination in Participants With Metastatic Prostate Cancer

A Study of Mezagitamab in Adults With Chronic Primary Immune Thrombocytopenia

Safety and Efficacy of MK-1200 in Participants With Advanced Solid Tumors (MK-1200-002)

A Study to Assess Efficacy and Safety of Empasiprubart Versus IVIg in Adults With CIDP

Trial of Therapeutic Cancer Vaccine OSE2101 in Patients With Non-Small Cell Lung Cancer and Secondary Resistance to Immune Checkpoint Inhibitor

Maridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea on Positive Airway Pressure Therapy

Collection and Storage of Tissue and Blood Samples From Patients With Cancer

A Study of GSK5764227 in Participants With Relapsed Small Cell Lung Cancer (SCLC)

A Study to Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either mFOLFIRINOX or NALIRIFOX Chemotherapies, in People With Pancreatic Cancer

A Prospective, Post-Market, Clinical Follow-up Study of the Incompass™ Total Ankle System

Ivonescimab in Comb. With FOLFOX in Advanced HER2 Neg. GEA