Clinical Trials in Pittsburgh

Showing 3201-3220 of 10,070 trials

Glyburide Advantage in Malignant Edema and Stroke Pilot

NCT01268683

The primary objective of this study is to assess the feasibility of enrolling, evaluating, and treating with glyburide for injection severe anterior circulation ischemic stroke participants, whether or not treated with standard of care intravenous (IV) recombinant tissue plasminogen activator (rtPA). Participants must be between 18-80 years of age, must have a baseline diffusion weighted image (DWI) lesion volume 82 -210 centimeters cubed (cm3), and time from symptom onset to start of study infusion must be ≤10 hour(hr). The secondary objectives are to assess the initial safety and tolerability, and pharmacokinetics (PK) /pharmacodynamics (PD) of glyburide in severe stroke participants, as well as to compare the clinical and magnetic resonance imaging (MRI) outcome data to benchmark data derived from published literature.

Ischemic Stroke

Remedy Pharmaceuticals, Inc.10 participantsStarted May 2011

Chicago, Illinois, United States • Baltimore, Maryland, United States • Boston, Massachusetts, United States +1 more locations

COMPLETED< 1 mile

Registry of Subjects With Drug Resistant Epilepsy and Treated With the VNS Therapy System.

NCT03529045

Multicenter global post-market registry of subjects diagnosed with drug resistant epilepsy and treated with the VNS Therapy System.

EpilepsySeizuresDrug Resistant Epilepsy

LivaNova827 participantsStarted Feb 2018

Grand Junction, Colorado, United States • Washington D.C., District of Columbia, United States • Orlando, Florida, United States +59 more locations

Glyburide Advantage in Malignant Edema and Stroke Pilot

Registry of Subjects With Drug Resistant Epilepsy and Treated With the VNS Therapy System.

Find Trials by Condition in Pittsburgh

Study to Evaluate the Efficacy, Safety, and Tolerability of Mirabegron in Older Adult Subjects With Overactive Bladder (OAB)

Observational Cohort Study of Patients With Castration-Resistant Prostate Cancer (CRPC)

A Pharmacokinetic Comparison of Three Butyrate Products

A Unique Micro Water Jet Technology Device Versus Standard Debridement in the Treatment of Diabetic Foot

The Study of Nasal Insulin in the Fight Against Forgetfulness (SNIFF)

Long-Term Extension Trial of Tildrakizumab to Prove Its Safety in Subjects With Psoriatic Arthritis Who Have Previously Completed Study With Tildrakizumab.

A Study of BI 765128 in Patients With an Eye Condition Called Diabetic Macular Ischemia Who Have Received Laser Treatment

Safety and Immunogenicity of RNA-based Vaccines Against SARS-CoV-2 Variants in Healthy Participants

Study of Pemetrexed + Platinum Chemotherapy With or Without Pembrolizumab (MK-3475) in Adults With Tyrosine Kinase Inhibitor- (TKI)-Resistant Epidermal Growth Factor Receptor- (EGFR)-Mutated Metastatic Non-squamous Non-small Cell Lung Cancer (NSCLC) (MK-3475-789/KEYNOTE-789)

Novapak Prospective Observational Clinical Trial

ME-344 and Bevacizumab in Previously Treated Metastatic Colorectal Cancer

Lentiviral Gene Therapy (Zamtocabtagene Autoleucel) LTFU

FPA150 in Patients With Advanced Solid Tumors

Adjunctive Fosfomycin for Treatment of Staphylococcus Aureus Bacteraemia

Erlotinib, Gemcitabine and Nab-Paclitaxel in Advanced Pancreatic Cancer

A Long-Term Safety Follow-Up Study for Patients Treat With WU-CART-007

A Randomized, Placebo-controlled, Double-blind Phase 2 Study With OSI-906 in Patients With Advanced HCC

Prospective, Multi-center, Single-arm Study of the Auryon Laser System for Treatment of Below-the-Knee (BTK) Arteries