Clinical Trials in Pittsburgh

Showing 2621-2640 of 21,047 trials

Type O Whole Blood and Assessment of Age During Prehospital Resuscitation Trial

NCT04684719

Open label, multi-center, pre-hospital randomized trial utilizing 10 level-1 trauma centers designed to determine the efficacy and safety of low titer whole blood resuscitation as compared to standard of care resuscitation in patients at risk of hemorrhagic shock and to appropriately characterize the hemostatic competency of whole blood relative to its age.

Hemorrhagic ShockTraumatic Injury

Jason Sperry1,020 participantsStarted Apr 2022

Birmingham, Alabama, United States • Louisville, Kentucky, United States • Jackson, Mississippi, United States +7 more locations

RECRUITING< 1 mile

Diabetes RElated to Acute Pancreatitis and Its Mechanisms: Metabolic Outcomes Using Novel CGM Metrics

NCT06401577

The DREAM-ON study will investigate whether continuous glucose monitoring (CGM) is useful to predict risk for developing diabetes mellitus (DM) and pre-diabetes mellitus (PDM), the need for insulin therapy among those who develop DM, and to determine whether CGM can provide insight into the pathophysiology and DM subtype among participants who have experienced an episode of acute pancreatitis (AP). Thus, the results of the DREAM-ON study could inform future clinical practice guidelines for the management AP as well as potentially extending the licensing authorization for CGM to include use in patients with pancreatogenic (Type 3c) DM.

Acute Pancreatitis

Milton S. Hershey Medical Center800 participantsStarted Oct 2024

Los Angeles, California, United States • Los Angeles, California, United States • Stanford, California, United States +10 more locations

Type O Whole Blood and Assessment of Age During Prehospital Resuscitation Trial

Diabetes RElated to Acute Pancreatitis and Its Mechanisms: Metabolic Outcomes Using Novel CGM Metrics

Find Trials by Condition in Pittsburgh

A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Metastatic Non-squamous NSCLC

A Trial to Evaluate the Efficacy and Safety of Different Doses of LEO 138559 in Adults With Moderate-to-severe Atopic Dermatitis

Ph2, Study to Assess the Safety and Efficacy of GPC 100 and Propranolol With and Without G-CSF for the Mobilization of Stem Cells in Patients With Multiple Myeloma Undergoing Autologous Stem Cell Transplant

A Study Evaluating AMG 193 in Combination With Other Therapies in Participants With Advanced Gastrointestinal, Biliary Tract, or Pancreatic Cancers With Homozygous Methylthioadenosine Phosphorylase (MTAP)-Deletion (MTAPESTRY 103)

Study of Bitopertin in Participants With EPP or XLP (APOLLO)

A Phase 1 Study of NRM-823 in Participants With Locally Advanced or Metastatic Refractory Solid Tumors

AMG 410 Alone and in Combination With Other Agents in Participants With KRAS Altered Advanced or Metastatic Solid Tumors

An Open-label Study (OLE) for Non-responders of VRDN-001-101 and VRDN-001-301

Tibulizumab Systemic Sclerosis Understanding and Response Evaluation (TibuSURE)

Efficacy and Safety of VB119 in Subjects With Membranous Nephropathy

Role of Prophylactic Postoperative Antibiotics in HoLEP

GATT-Patch Versus SURGICEL® Original in Minimally Invasive Liver and Gallbladder Surgery

Evaluation of ELU42 Topical Spray for the Treatment of Diabetic Foot Ulcers

A Study to Assess Efficacy and Safety of LB54640 in Patients With Hypothalamic Obesity

A Phase 4 Clinical Study to Investigate the Effectiveness and Safety of Skin Resurfacing

Breathe Easier With Tadalafil Therapy for Dyspnea in COPD-PH

Cardiovascular Kidney and Metabolic Health Assessment and Patient Empowerment

A Safety and Efficacy Extension Study of Pertuzumab in Patients With Solid Tumors Previously Enrolled in a Hoffmann-La Roche-Sponsored Pertuzumab Clinical Trial