Clinical Trials in Pittsburgh

Showing 2461-2480 of 10,050 trials

A Study Evaluating the Safety, Tolerability, and Efficacy of EVO756 in Adults With Chronic Inducible Urticaria

NCT06603220

This phase 2a trial will evaluate the safety and efficacy of EVO756 in subjects with chronic inducible urticaria, including symptomatic dermographism and cold urticaria.

Chronic Inducible Urticaria

Evommune, Inc.30 participantsStarted Aug 2024

Birmingham, Alabama, United States • Los Angeles, California, United States • Sacramento, California, United States +15 more locations

Active Not RecruitingPhase 1< 1 mile

Allogeneic Regulatory Dendritic Cell (DCreg) Renal Study

NCT03726307

This study will evaluate the safety and feasibility of treatment involving a single infusion of donor-derived regulatory dendritic cells (DCreg) in first time, living donor renal transplant recipients. DCreg will be prepared from monocytes obtained by leukapheresis from prospective (non-mobilized) living kidney donors and infused into the respective recipients 7 days before renal transplantation. This study will enroll 28 subjects (14 recipients, 14 donors). The duration of follow-up will be: * 1 week following the leukapheresis procedure for donors and * 2 years following their DCreg infusion for kidney recipients.

Kidney TransplantRenal Transplant Recipients

Angus W. Thomson PhD DSc28 participantsStarted Apr 2019

Pittsburgh, Pennsylvania, United States

A Study Evaluating the Safety, Tolerability, and Efficacy of EVO756 in Adults With Chronic Inducible Urticaria

Allogeneic Regulatory Dendritic Cell (DCreg) Renal Study

Find Trials by Condition in Pittsburgh

A Study of Unesbulin in Participants With Advanced Leiomyosarcoma (LMS)

A Study for Kidney Transplant Recipients at High-Risk of Cytomegalovirus Infection

Open-Label Study of the CDK4/6 Inhibitor SPH4336 in Subjects With Locally Advanced or Metastatic Liposarcomas

Investigating Geographic Atrophy Insights (i-GAIN) Natural History Study

Study of AZD0466 Monotherapy or in Combination in Patients With Advanced Haematological Malignancies

A Follow-On Study of Donanemab (LY3002813) With Video Assessments in Participants With Alzheimer's Disease (TRAILBLAZER-EXT)

The Role of Electrophysiology Testing in Survivors of Unexplained Cardiac Arrest

A Study of TAK-079 in Adults With Persistent/Chronic Primary Immune Thrombocytopenia

Saroglitazar Magnesium for Treatment of Primary Biliary Cholangitis

Couples Motivational Interviewing to Reduce Drug Use and HIV Risk in Vulnerable Male Couples

Dose Escalation and Dose Expansion Study of Tirabrutinib in Combination With Other Targeted Anti-cancer Therapies in Adults With B-cell Malignancies

Autosomal Dominant Polycystic Kidney Disease (ADPKD) Study

A Study to Investigate the Safety and Immunogenicity of the Quadrivalent Influenza mRNA Vaccines in Adults Aged 18 Years and Above

Study of Long Term Safety and Clinical Outcomes of Idursulfase IT and Elaprase Treatment in Pediatric Participants Who Have Completed Study HGT-HIT-094

Multi-Center Adolescent Clavicle Fracture Trial: Operative vs. Non-Operative Treatment

RemI for Post-Bariatric Surgery Weight Regain

EluPro Antibiotic-Eluting BioEnvelope Registry

Proton Radiation Therapy (RT) for the Treatment of Pediatric Rhabdomyosarcoma