Clinical Trials in Philadelphia

Showing 1081-1100 of 9,968 trials

Clinical Transcriptomics in Systemic Vasculitis (CUTIS)

NCT03004326

Multi-center observational study to evaluate the histopathology and transcriptome of cutaneous lesions in patients with several different types of vasculitis.

Cryoglobulinemic Vasculitis (CV)Drug-induced VasculitisEosinophilic Granulomatosis With Polyangiitis (EGPA)+7 more

Peter Merkel50 participantsStarted Jan 2017

Los Angeles, California, United States • Boston, Massachusetts, United States • Rochester, Minnesota, United States +7 more locations

COMPLETEDPhase 4< 1 mile

Antibiotic Prophylaxis in Patients Undergoing Elective Total Knee Arthroplasty- Multi-center Trial

NCT03283878

The Antibiotic Prophylaxis in Patients Undergoing Elective Total Knee Arthroplasty (TKA): Multi-Center Trial is a study that will compare the effectiveness of various perioperative strategies for antibiotic delivery as prophylaxis for periprosthetic joint infections (PJI) and surgical site infection in elective primary TKA. The investigators hypothesize that a single dose of prophylactic antibiotic administered within 60 minutes before the incision is not an effective way to prevent PJI in elective primary total knee arthroplasty (TKA). The investigators also hypothesize that the prolonged delivery (24 hours) of antibiotic prophylaxis after surgery does not further reduce the incidence of PJI in elective primary TKA. Duke University is the only site recruiting both primary total knee arthroplasty and unilateral knee arthroplasty.

Arthropathy of KneeAntibiotic Prophylaxis

Duke University1,770 participantsStarted Oct 2017

San Francisco, California, United States • Atlanta, Georgia, United States • Towson, Maryland, United States +11 more locations

Clinical Transcriptomics in Systemic Vasculitis (CUTIS)

Antibiotic Prophylaxis in Patients Undergoing Elective Total Knee Arthroplasty- Multi-center Trial

Find Trials by Condition in Philadelphia

UPenn Observational Research Repository on Neurodegenerative Disease

US IDE Study of the Contour NEurovasCular System™ for IntraCranial Aneurysm Repair

A Clinical Trial of Early Ventilation in Amyotrophic Lateral Sclerosis (EVENT ALS)

Testing Whether the Addition of Carboplatin Chemotherapy to Cabazitaxel Chemotherapy Will Improve Outcomes Compared to Cabazitaxel Alone in People With Castrate-Resistant Prostate Cancer That Has Spread Beyond the Prostate to Other Parts of the Body

A Research Study to See How Well CagriSema Compared to Semaglutide, Cagrilintide and Placebo Lowers Blood Sugar and Body Weight in People With Type 2 Diabetes Treated With Metformin With or Without an SGLT2 Inhibitor

Using Biomarker Tests to Select and Test New, Personalized Treatments for Extensive Stage Small Cell Lung Cancer, PRISM Study

A Study of Neoadjuvant Atezolizumab Plus Chemotherapy Versus Placebo Plus Chemotherapy in Patients With Resectable Stage II, IIIA, or Select IIIB Non-Small Cell Lung Cancer (IMpower030)

Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Children and Adolescents

A Phase 1 in Patients With HLA-A*0201+ and WT1+ Recurrent/Metastatic Cancers

Equity in Modifying Plaque Of WomEn With UndeRtreated Calcified Coronary Artery Disease

A Phase 1 Study in Patients With HPV16+ Recurrent/ Metastatic Head and Neck Squamous Cell Carcinoma

A Clinical Study of MK-2870 Alone or With Other Treatments to Treat Gastrointestinal Cancers (MK-9999-02A)

A Study of PF-08046052/SGN-EGFRd2 in Advanced Solid Tumors

Nivolumab + Docetaxel + ADT in mHSPC Patients With DDRD or Inflamed Tumors

DBT Skills Groups for Veterans at High Risk for Suicide Attempt

Evaluating the Long-Term Safety and Tolerability of Efgartigimod PH20 SC Administered Subcutaneously in Patients With Generalized Myasthenia Gravis

JAB-30355 in Patients With Advanced Solid Tumors Harboring TP53 Y220C Mutation

A Single-Ascending and Repeated Dose Study of LY3849891 in Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)