Clinical Trials in Philadelphia

Showing 1021-1040 of 20,904 trials

A Pragmatic Trial of an Active Choice Nudge for Generalist or Specialist Palliative Care for Seriously Ill Inpatients

NCT05502861

This stepped-wedge, cluster-randomized pragmatic trial among six hospitals at University of Pennsylvania Health System will test a behavioral intervention embedded within the electronic health record that nudges hospital clinicians to either provide palliative care (PC) themselves (generalist PC) or consult specialists (specialty PC) for inpatients at high risk of death within 6 months. The trial will evaluate the intervention's effect compared to usual care on the primary outcome of hospital-free days through 6 months, and other patient-centered, clinical, and economic outcomes. The trial also includes an embedded mixed methods study to understand clinician and hospital contextual factors that influence the intervention's uptake.

Palliative Care

University of Pennsylvania18,884 participantsStarted Nov 2023

Philadelphia, Pennsylvania, United States

RECRUITINGNA< 1 mile

GORE® Ascending Stent Graft in the Treatment of De Novo Type A Aortic Dissections

NCT06827990

To assess the safety and effectiveness of the ASG device in the treatment of de novo Type A aortic dissections.

Aortic Dissection

W.L.Gore & Associates112 participantsStarted Sep 2025

Birmingham, Alabama, United States • Los Angeles, California, United States • Gainesville, Florida, United States +13 more locations

A Pragmatic Trial of an Active Choice Nudge for Generalist or Specialist Palliative Care for Seriously Ill Inpatients

GORE® Ascending Stent Graft in the Treatment of De Novo Type A Aortic Dissections

Find Trials by Condition in Philadelphia

A Study Evaluating the Efficacy and Safety of Ralinepag to Improve Treatment Outcomes in PAH Patients

NP-G2-044 as Monotherapy and Combination Therapy in Patients With Advanced or Metastatic Solid Tumor Malignancies

N2004-04: Fenretinide LXS in Treating Patients With Recurrent, Refractory, or Persistent Neuroblastoma

Penn Produce Prescription and Chronic Kidney Disease Study

Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response

A Study of the Safety and Effectiveness of the Mentor Larger Size MemoryGel Ultra High Profile Breast Implants in Subjects Who Are Undergoing Primary Breast Reconstruction or Revision Reconstruction

SIMPLAAFY Clinical Trial

An Expanded Access Program of Cretostimogene Grenadenorepvec for Treatment of NMIBC for Patients Unresponsive to BCG

A Study of Inclisiran to Prevent Cardiovascular Events in High-risk Primary Prevention Patients.

Coronary Computed Tomography Study to Assess the Effect of Inclisiran in Addition to Maximally Tolerated Statin Therapy on Atherosclerotic Plaque Progression in Participants With a Diagnosis of Non-obstructive Coronary Artery Disease Without Previous Cardiovascular Events

Health Related Quality of Life Following Hepatectomy for Colorectal Liver Metastasis: Global and Disease Specific Changes Over Time

A Study to Assess BMS-986458 Alone and in Combination With Anti-lymphoma Agents in Relapsed/Refractory Non-Hodgkin Lymphomas

Savolitinib vs. Sunitinib in MET-driven PRCC.

Clinical Decision Support Tool in PARDS Pilot Study

A Study of ZW251 in Participants With Advanced Solid Tumors

Study of Voicing My CHOiCES as a Tool for Advanced Care Planning in Young Adults With Cancer

Study of Plozasiran (ARO-APOC3) in Adults With Mixed Dyslipidemia

A Trial to Investigate the Safety and Efficacy of Intra-articular 4P004 Injection in Subjects With Knee Synovitis and Osteoarthritis