Clinical Trials in Philadelphia

Showing 10201-10220 of 17,926 trials

FES Assisted Cycling in Children With CP

NCT04688424

This project proposes to assess if Functional Electrical Stimulation (FES) assisted cycling can improve the cycling ability, muscle strength, cardiovascular health, quality of life, self perception and functional mobility of adolescents with CP better than a volitional cycling program or a non-intervention control group.

Cerebral Palsy Spastic Diplegia

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)39 participantsStarted Apr 2008

Philadelphia, Pennsylvania, United States

COMPLETEDPhase 2< 1 mile

The Effect of Sorafenib on Portal Pressure

NCT01714609

Sorafenib is approved by the US FDA for the treatment of unresectable (can not operate) liver cancer and for renal cell carcinoma. Sorafenib is a drug that inhibits the growth of cancer cells and prevents the formation of new blood vessels that would otherwise help the cancer spread. Studies in experimental animals have shown that sorafenib may also lower portal vein pressure (the pressure of the blood passing from the intestine through the liver.) This study seeks to determine if sorafenib lowers the blood pressure in liver blood vessels (portal vein pressure) in patients with cirrhosis who have high portal vein pressure. The study will also obtain information whether sorafenib is safe in this patient population. Half of the patients will be given sorafenib and half will be given a placebo (a pill without any medicine in it.) This allows a comparison of the reactions of people who take sorafenib to those who do not.

Clinically Significant Portal Hypertension

Yale University10 participantsStarted Aug 2011

New Haven, Connecticut, United States • West Haven, Connecticut, United States • Boston, Massachusetts, United States +3 more locations

FES Assisted Cycling in Children With CP

The Effect of Sorafenib on Portal Pressure

Find Trials by Condition in Philadelphia

A Phase Ib/II Study of BYL719 and Cetuximab in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

Visual Restoration for Hemianopia

Open-label Long Term (52 Weeks) Safety and Tolerability of Agomelatine Sublingual Tablets in Major Depressive Disorder (MDD)

Efficacy, Safety and Tolerability of Agomelatine in the Treatment of Major Depressive Disorder

Intervention to Promote Weight Loss in Latinas At-risk for Diabetes

Efficacy and Safety of AEB071 Versus Tacrolimus in Combination With Mycophenolate Acid Sodium, Basiliximab and Steroids in Preventing Acute Rejection After Kidney Transplantation

COMPLETE: International Acute Ischemic Stroke Registry With the Penumbra System Aspiration Including the 3D Revascularization Device

Efficacy, Safety and Tolerability of Agomelatine Sublingual Tablets in the Treatment of Major Depressive Disorder

Efficacy, Safety and Tolerability of Agomelatine in the Treatment of Major Depressive Disorder

Crizotinib and Ganetespib (STA-9090) in ALK Positive Lung Cancers

Safety, Tolerability, and Efficacy of AEB071 in the Treatment of Uveitis

A Study of Carboplatin and Paclitaxel With or Without MEDI-575 in Untreated, Advanced Non-Small Cell Lung Cancer

A Dose Escalation Study in Solid Tumors and a Dose Expansion Study of PRN1371 in Adult Patients With Metastatic Urothelial Carcinoma

A Study of Palonosetron for the Prevention of Chemotherapy-Induced Nausea and Vomiting (CINV) in Participants Who Have Experienced CINV(Chemotherapy-Induced Nausea and Vomiting) During the Previous Cycle of Low Emetogenic Chemotherapy (LEC)

A Dose Finding Study of AEB071 Assessing Psoriasis Area and Severity Index in Patients With Plaque Psoriasis

Open-label, Long-term Safety Extension Study of AFQ056 in Parkinson's Patients With L-dopa Induced Dyskinesias

Efficacy, Safety, Tolerability, and Pharmacokinetics of Sotrastaurin Combined With Tacrolimus vs. a Mycophenolic Acid-tacrolimus Regimen in Renal Transplant Patients

An Efficacy and Safety Study of Alirocumab in Children and Adolescents With Homozygous Familial Hypercholesterolemia