Clinical Trials in Philadelphia

Showing 881-900 of 9,968 trials

Study to Evaluate the Safety & Tolerability of MRT5005 Administered by Nebulization in Adults With Cystic Fibrosis

NCT03375047

This Phase 1/2, first-in-human study evaluated the safety and tolerability of single and multiple escalating doses of MRT5005 administered by nebulization to the respiratory tract of adult subjects with cystic fibrosis (CF).

Cystic Fibrosis

Sanofi42 participantsStarted May 2018

Birmingham, Alabama, United States • Denver, Colorado, United States • Gainesville, Florida, United States +13 more locations

COMPLETED< 1 mile

Cardiovascular Effects of CART Cell Therapy

NCT04026737

This is an observational study aiming to prospectively define the rate of occurrence, natural history and progression of cardiac dysfunction in adults, and to identify the patients at high risk of developing cardiovascular events. The study enrolls patients prior to infusion with CART cell therapy and follows them with serial echocardiography, cardiac biomarkers, clinical data, and quality of life questionnaire.

LeukemiaLymphomaCardiotoxicity+2 more

Abramson Cancer Center at Penn Medicine44 participantsStarted Jul 2019

Philadelphia, Pennsylvania, United States

Study to Evaluate the Safety & Tolerability of MRT5005 Administered by Nebulization in Adults With Cystic Fibrosis

Cardiovascular Effects of CART Cell Therapy

Find Trials by Condition in Philadelphia

Open-label Extension Study of Seralutinib in Adult Subjects With PAH (PROSERA-EXT)

A Study of BH-30643 in Subjects With Locally Advanced or Metastatic NSCLC Harboring EGFR and/or HER2 Mutations

Suppression of Ovarian Function With Either Tamoxifen or Exemestane Compared With Tamoxifen Alone in Treating Premenopausal Women With Hormone-Responsive Breast Cancer

A Longitudinal Observational Study of the Natural History and Management of Patients With HCC

Genetic Mutational Analysis of Saliva or Buccal Mucosa Samples From Patients With Embryonal or Alveolar Rhabdomyosarcoma

A Study on the Effects of Exercise on Side Effects From Treatment for Gastrointestinal Cancers

ADP-A2M4CD8 as Monotherapy or in Combination With Either Nivolumab or Pembrolizumab in HLA-A2+ Subjects With MAGE-A4 Positive Tumors (SURPASS)

An Open-Label ProSpective MultiCENTer Study to Evaluate Safety and Tolerability of Dry Powder Inhaled Treprostinil in PH

Study of HRO761 Alone or in Combination in Cancer Patients With Specific DNA Alterations Called Microsatellite Instability or Mismatch Repair Deficiency.

Study of Efficacy and Safety of Investigational Treatments in Patients With Moderate to Severe Hidradenitis Suppurativa

A Prospective Sub-Study of the Global Hypophosphatasia Registry

CLOZAPINE Response in Biotype-1

FX Shoulder Prospective Clinical Study

Intermuscular Coherence as a Biomarker for ALS

A Study of Abemaciclib (LY2835219) Plus Tamoxifen or Abemaciclib Alone in Women With Metastatic Breast Cancer

A Study Evaluating the Efficacy and Safety of Vixarelimab in Participants With Idiopathic Pulmonary Fibrosis and in Participants With Systemic Sclerosis-Associated Interstitial Lung Disease

Avapritinib Rollover Study

Global Registry for Endovascular Aortic Treatment (GREAT)