Clinical Trials in Philadelphia

Showing 8801-8820 of 15,860 trials

HSPPC-96 Vaccine With Temozolomide in Patients With Newly Diagnosed GBM

NCT00905060

This phase II trial studies the side effects and how well HSPPC-96 (vitespen) and temozolomide work in treating patients with newly diagnosed glioblastoma multiforme. Vaccines made from a person's tumor cells and heat shock protein peptide may help the body to build an effective immune response to kill tumor cells. Drugs used in chemotherapy, such as temozolomide, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving HSPPC-96 (vitespen) together with temozolomide may kill more tumor cells.

Brain and Central Nervous System Tumors

University of California, San Francisco70 participantsStarted Jun 2009

San Francisco, California, United States • Miami, Florida, United States • Chicago, Illinois, United States +6 more locations

TERMINATEDNA< 1 mile

Sentus QP - Extended CRT Evaluation With Quadripolar Left Ventricular Leads

NCT02290028

The QP ExCELs study is designed to confirm safety and efficacy of the BIOTRONIK Sentus OTW QP left ventricular leads to satisfy FDA requirements for regulatory approval of the leads in the US. The Sentus OTW QP leads received FDA approval on May 4, 2017. Long-term safety of the BIOTRONIK Sentus OTW QP left ventricular leads will be confirmed during the ongoing post approval phase (US sites only). A protocol update was implemented on September 6, 2019 to transition the long-term follow up for the ongoing Sentus QP Study to a new EP PASSION real-world data methodology.

Heart Failure

Biotronik SE & Co. KG2,226 participantsStarted Dec 2014

Fairhope, Alabama, United States • Anchorage, Alaska, United States • Chula Vista, California, United States +116 more locations

HSPPC-96 Vaccine With Temozolomide in Patients With Newly Diagnosed GBM

Sentus QP - Extended CRT Evaluation With Quadripolar Left Ventricular Leads

Find Trials by Condition in Philadelphia

Mirabegron in Achalasia: A Clinical and Manometric Proof of Concept Pilot Study

Study to Evaluate a Single Dose of Apixaban in Pediatric Participants at Risk for a Thrombotic Disorder

Long-term Study in US Cystic Fibrosis Patients Receiving Digestive Enzyme Supplements to Assess Narrowing of the Large Intestine Causing Adverse Intestinal Symptoms (Fibrosing Colonopathy)

Longitudinal Surveillance Study of the 4-SITE Lead/Header System

FMISO PET/CT Imaging Trial for Assessing Hypoxia in Soft Tissue Sarcomas

Early Elimination of Premature Ventricular Contractions in Heart Failure

Outcomes Related to COVID-19 Treated With Hydroxychloroquine Among In-patients With Symptomatic Disease

Safety and Maintenance of Effect of Ziprasidone Plus a Mood Stabilizer in Bipolar I Disorder (Manic or Mixed)

Intramuscular Peramivir in Subjects With Uncomplicated Acute Influenza

Phase IIb Safety and Efficacy Study of Four Dose Regimens of BAY1021189 in Patients With Heart Failure With Reduced Ejection Fraction Suffering From Worsening Chronic Heart Failure (SOCRATES-REDUCED)

A Study to Investigate the Efficacy and Safety of Lusutrombopag (S-888711) Tablets Administered to Adults With Immune Thrombocytopenia (ITP)

Short Term Observational Study in DEB Patients

Natural History Study of Children With Metachromatic Leukodystrophy

Evaluation of the Long-term Safety, Pharmacodynamics, and Exploratory Efficacy of GZ/SAR402671 in Treatment-Naïve Adult Male Patients With Fabry Disease

Safety, PK and Effectiveness of IV Peramivir Versus Oseltamivir in Pediatric Subjects With Uncomplicated Influenza

Ceprotin Treatment Registry

Efficacy and Safety of BCX7353 to Prevent Angioedema Attacks in Subjects With Hereditary Angioedema

Effect of Sulodexide in Overt Diabetic Nephropathy