Clinical Trials in Philadelphia

Showing 8541-8560 of 15,860 trials

Reducing Cell Phone Use While Driving Among High Risk UBI Auto Policy Holders

NCT04587609

Insurance User Based Insurance (UBI) users will be invited to participate in a randomized control trial where they will be randomized into 1 of 4 arms: (Arm 1) standard UBI, (Arm 2) Standard UBI + Free phone mounts (Arm 3) Commitment + Habit Tips, (Arm 4) Gamification + Social Competition,(Arm 5) Contest Financial Incentives. Each successive arm will experience all of the elements that the lower-numbered arms will.

Distracted DrivingDriving Impaired

University of Pennsylvania1,668 participantsStarted Mar 2021

Philadelphia, Pennsylvania, United States

COMPLETEDPhase 3< 1 mile

A Phase 3 Study of VX-445 Combination Therapy in Cystic Fibrosis (CF) Subjects Heterozygous for F508del and a Gating or Residual Function Mutation (F/G and F/RF Genotypes)

NCT04058353

This study will evaluate the efficacy, safety and pharmacodynamics of elexacaftor (ELX, VX-445) in triple combination (TC) with tezacaftor (TEZ) and ivacaftor (IVA) in subjects with cystic fibrosis (CF) who are heterozygous for F508del and a gating or residual function mutation (F/G and F/RF genotypes).

Cystic Fibrosis

Vertex Pharmaceuticals Incorporated271 participantsStarted Aug 2019

Birmingham, Alabama, United States • Tucson, Arizona, United States • Long Beach, California, United States +90 more locations

Reducing Cell Phone Use While Driving Among High Risk UBI Auto Policy Holders

A Phase 3 Study of VX-445 Combination Therapy in Cystic Fibrosis (CF) Subjects Heterozygous for F508del and a Gating or Residual Function Mutation (F/G and F/RF Genotypes)

Find Trials by Condition in Philadelphia

A Study to Evaluate the Safety and Efficacy of Tocilizumab in Patients With Severe COVID-19 Pneumonia

Testing AZD4547 as a Potential Targeted Treatment in Cancers With FGFR Genetic Changes (MATCH-Subprotocol W)

SPIRIT 1: Efficacy and Safety Study of Relugolix in Women With Endometriosis-Associated Pain

Clobetasol Topical Oil for Children With Moderate to Severe Atopic Dermatitis

Long-Term Analgesic Efficacy And Safety Of Tanezumab Alone Or In Combination With Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) Versus NSAIDs Alone In Patients With Osteoarthritis Of The Knee Or Hip

ITI-007 for the Treatment of Agitation in Patients With Dementia, Including Alzheimer's Disease

Safety and Efficacy Study of Sotagliflozin on Glucose Control in Participants With Type 2 Diabetes, Moderate Impairment of Kidney Function, and Inadequate Blood Sugar Control

Whole Lung IMRT in Children and Adults With Synovial Sarcoma and Lung Metastases

A Study of Elotuzumab in Combination With Pomalidomide and Low Dose Dexamethasone and Elotuzumab in Combination With Nivolumab in Patients With Multiple Myeloma Relapsed or Refractory to Prior Treatment With Lenalidomide.

A Study of Oral AMN107 in Adults With Chronic Myelogenous Leukemia (CML) or Other Hematologic Malignancies

SPIRIT 2: Efficacy and Safety Study of Relugolix in Women With Endometriosis-Associated Pain

Non-Inferiority Study of the FRESCA Airbox Positive Airway Pressure System

Multicenter Study Of CPX-1 (Irinotecan HCl: Floxuridine) Liposome Injection In Patients With Advanced Colorectal Cancer

Rectal Safety and Acceptability Study of Tenofovir 1% Gel

An Extension Study of the Safety and Anti-leukemic Effects of Imatinib Mesylate in Participants With Philadelphia Chromosome-positive Chronic Myeloid Leukemia in Blast Crisis

A Trial Evaluating the Efficacy and Safety of HLD200 in Children With ADHD

A Study to Examine the Efficacy and Safety of REGN5069 in Patients With Pain Due to Osteoarthritis of the Knee

Long Term Study of Canakinumab (ACZ885) in Patients With Gout