Clinical Trials in Philadelphia

Showing 7161-7180 of 15,860 trials

Thoracolumbar Burst Fractures Study Comparing Surgical Versus Non-surgical Treatment

NCT02827214

Thoracolumbar (TL) burst fractures in neurologically intact patients account for approximately 45% of all TL spine injuries. Despite being common fractures, there is significant variability in treatment recommendations encompassing surgery and non-surgical treatment options. The controversy regarding optimal treatment for these injuries is fueled by several studies which suggest a potential benefit to surgical treatment in the realm of patient satisfaction, and the overall socio-economic burden of treatment while other studies demonstrate improved outcomes and lower morbidity with non-surgical treatment. This study aims to perform a prospective cohort analysis investigating the clinical outcome of various treatment alternatives for patients with A3/A4 fractures in the thoracolumbar region. A cost-effectiveness analysis will also be performed to identify costs and benefits of each treatment option. More specifically a sub-group analysis will be performed for this group of patients, which have equipoise in regards to patients treatment, as decided by a blinded review panel.

Thoracolumbar Burst Fracture

AO Innovation Translation Center213 participantsStarted Oct 2016

San Diego, California, United States • East Syracuse, New York, United States • Philadelphia, Pennsylvania, United States +11 more locations

WITHDRAWNNA< 1 mile

Study Tests Whether a Standardized LVR Performed With the Blue Egg Device Improves Cardiopulmonary Exercise Capacity

NCT00326690

The purpose of the present prospective, randomized study is to investigate the clinical effectiveness of standardized left ventricular reconstruction surgery (LVR). In order to standardize the procedure, the operation will be performed with the Blue Egg, manufactured by BioVentrix, a subsidiary of CHF Technologies, Inc.

Congestive Heart FailureIschemic CardiomyopathyCoronary Artery Disease+1 more

BioVentrixStarted Nov 2005

Los Angeles, California, United States • St. Petersburg, Florida, United States • Baltimore, Maryland, United States +7 more locations

Thoracolumbar Burst Fractures Study Comparing Surgical Versus Non-surgical Treatment

Study Tests Whether a Standardized LVR Performed With the Blue Egg Device Improves Cardiopulmonary Exercise Capacity

Find Trials by Condition in Philadelphia

Contrast Ultrasound Detection of Sentinel Lymph Nodes

Safety and Efficacy Study of AMG 820 and Pembrolizumab Combination in Select Advanced Solid Tumor Cancer

A Phase 3 Study of NI-071 in Participants With Rheumatoid Arthritis (RADIANCE)

Effectiveness and Safety of BMS-986165 Compared to Placebo and Active Comparator in Participants With Psoriasis

A Study of Baricitinib (LY3009104) in Participants With Systemic Lupus Erythematosus

Evaluation Of Clostridium Difficile Vaccine Lot Consistency In Healthy Adults 65 To 85 Years Of Age

Certolizumab in Combination With Chemotherapy for Patients With Stage IV Lung Adenocarcinomas

Pembrolizumab, Belantamab and Dexamethasone in Refractory Multiple Myeloma.

Assessing the Efficacy and Safety of Brolucizumab Versus Aflibercept in Patients With Visual Impairment Due to Macular Edema Secondary to Branch Retinal Vein Occlusion

A Study of Atezolizumab in Combination With Bevacizumab Versus Sunitinib in Participants With Untreated Advanced Renal Cell Carcinoma (RCC)

Study to Evaluate the Safety and Preliminary Efficacy of IDCT, a Treatment for Symptomatic Lumbar Intervertebral Disc Degeneration

Outcome pRognostication of Acute Brain Injury With the NeuroloGical Pupil indEx

Exercise Trial in Chronic Kidney Disease

Rectal Microbicide Acceptability, Tolerability and Adherence

Neuro RX Gamma - Pivotal Phase

A Study to Assess How Well Certolizumab Pegol Works in Patients With Moderate to Severe Plaque Psoriasis as Part of Routine Clinical Practice

Cholangioscopy in Primary Sclerosing Cholangitis (PSC)

Coronavirus Disease (COvid-)19 REgistry on THROMBOSIS Complications